S1701

Anti-SDCBP antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution

• 别名: Anti-MDA-9, Anti-Melanoma differentiation associated protein-9, Anti-Pro-TGF-alpha cytoplasmic domain-interacting protein 18, Anti-Scaffold protein Pbp1, Anti-ST1, Anti-SYCL, Anti-Syndecan binding protein (syntenin), Anti-Syntenin, Anti-TACIP18
• 分類程式碼代碼: 12352203
• NACRES: NA.41

属性

• 生物源: rabbit
• 品質等級: 200
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 形狀: buffered aqueous solution
• 分子量: antigen ~30 kDa
• 物種活性: mouse, human, rat
• 濃度: ~1.0 mg/mL
• 技術: immunoprecipitation (IP): 10-20 μg using lysates of human HeLa cells; indirect immunofluorescence: 2-5 μg/mL using human HeLa cells; western blot: 2-4 μg/mL using whole extract of human HEK-293T cells, rat NRK cells, or mouse Neuro-2a cells
• UniProt登錄號: O00560
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... SDCBP(6386)

说明

一般說明

Syndecan binding protein (SDCBP), also known as syntenin and melanoma differentiation associated gene-9 (mda-9), was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. SDCBP contains tandemly repeated PDZ domains that binds the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. SDCBP is primarily localized to membrane associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus.

應用

Anti-SDCBP antibody produced in rabbit has been used in:

• enzyme linked immuno sorbent assay (ELISA)
• immunoblotting
• immunocytochemistry

生化／生理作用

Syndecan binding protein (SDCBP) regulates cytoskeletal-membrane organization, cell adhesion, protein trafficking and the activation of transcription factors. SDCBP promotes metastasis in human melanoma cells by activating c-Src.

外觀

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: nwg
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable