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應用
Streptokinase (SK) is commonly used as a thrombolytic agent in the therapy of ischemic stroke. This therapy carries the important risk of intracerebral hemorrhage. Streptokinase is also used in the treatment of complicated parapneumonic effusions and empyema where adverse reactions, allergic type, are rare. The product has been used to measure SK activity in brain heart infusion culture supernatant fluids of the various wild-type and mutant strains of Streptococcus dysgalactiae subsp. Equisimilis.
生化／生理作用
Streptokinase C is an extracellular enzyme that is produced by various strains of β-hemolytic streptococci. It is a single-chain polypeptide that exerts its fibrinolytic action indirectly by activating the circulatory plasminogen.
單位定義
One unit will liquify a standard clot of fibrinogen, plasminogen, and thrombin at pH 7.5 at 37 °C in 10 min.
外觀
Supplied as a frozen solution containing 60 mM phosphate buffer and 0.6 M glutamate. Albumin-free
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Kerstin Steiner et al.
Infection and immunity, 70(7), 3627-3636 (2002-06-18)
Synthesis of the plasminogen activator streptokinase (SK) by group A streptococci (GAS) has recently been shown to be subject to control by two two-component regulators, covRS (or csrRS) and fasBCA. In independent studies, response regulator CovR proved to act as
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