推荐产品
物種活性
mouse
包裝
kit of 96 wells (12 strips x 8 wells)
技術
ELISA: suitable
assay range
inter-assay cv: <10%
intra-assay cv: <12%
檢測方法
colorimetric
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
mouse ... Olr1(108078)
一般說明
The antibody pair provided in this kit recognizes mouse Oxidized Low-density Lipoprotein Receptor 1.
應用
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
生化／生理作用
Oxidized low-density lipoprotein receptor 1 (OLR1), also referred as Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1), acts as a scavenger receptor for oxidized low-density lipoprotein (ox-LDL). It is essential for formation and progression of atherosclerotic plaques. Therefore, mutation in the gene increases the risk of susceptibility to atherosclerotic-related diseases. In addition, genetic variation in the gene leads to myocardial infarction. Serum concentration of OLR1 serves as an efficient biomarker of intracerebral hemorrhage (ICH).
訊號詞
Warning
危險聲明
防範說明
危險分類
Met. Corr. 1
儲存類別代碼
8A - Combustible corrosive hazardous materials
閃點（°F）
Not applicable
閃點（°C）
Not applicable
LOX-1 and atherosclerotic-related diseases.
Jin P and Cong S
Clinica Chimica Acta; International Journal of Clinical Chemistry, 491, 24-29 (2019)
Oxidized LDL receptor gene (OLR1) is associated with the risk of myocardial infarction
Tatsuguchi M, et al.
Biochemical and Biophysical Research Communications, 303(1), 247-250 (2003)
Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels as a Biomarker of Acute Intracerebral Hemorrhage
Inoue T, et al.
Journal of Stroke and Cerebrovascular Diseases : The Official Journal of National Stroke Association, 28(2), 490-494 (2019)
Akshay Sood et al.
The Journal of asthma : official journal of the Association for the Care of Asthma, 51(5), 459-466 (2014-01-23)
Adipose tissue produces adiponectin, an anti-inflammatory protein. High systemic total adiponectin is associated with a low risk for incident asthma but the association with lung adiponectin is not known. Our objective was to evaluate the association between sputum total adiponectin
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