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物種活性
rat, mouse, human
包裝
kit of 96 wells (12 strips x 8 wells)
技術
ELISA: suitable
enzyme immunoassay: suitable
輸入
sample type plasma
sample type cell lysate
sample type serum
sample type culture supernatant(s)
assay range
inter-assay cv: <15%
intra-assay cv: <10%
sensitivity: 2 pg/mL
standard curve range: 1-10000 pg/mL
檢測方法
colorimetric
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
human ... INHBB(3625)
一般說明
Inhibin-B (INHBB) is a heterodimeric glycoprotein with disulfide-linkage. It is produced by granulosa cells in the ovary. The INHBB gene is mapped to human chromosome 2q14.2. Inhibin-B inhibits follicle-stimulating hormone (FSH) secretion and synthesis. It may serve in diagnosing testicular function and as an indicator of Sertoli cell numbers and function. Inhibin B may serve as a marker for spermatogenesis.
The Inhibin B Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting Inhibin B peptide based on the principle of Competitive Enzyme Immunoassay. EIA-INB-1 targets the β B subunit, and therefore theoretically detects Activin B and Activin AB in addition to Inhibin B.
The Inhibin B Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting Inhibin B peptide based on the principle of Competitive Enzyme Immunoassay. EIA-INB-1 targets the β B subunit, and therefore theoretically detects Activin B and Activin AB in addition to Inhibin B.
免疫原
Inhibin-B, synthetic peptide
應用
Inhibin-B EIA Kit has been used in quantification of Inhibin-B using enzyme-linked immunosorbent assay (ELISA) in Zika virus-infected human Sertoli cells (HSerC) and 8-week-old mice.
訊號詞
Warning
危險聲明
防範說明
危險分類
Met. Corr. 1
儲存類別代碼
8A - Combustible corrosive hazardous materials
European journal of endocrinology, 145(5), 561-571 (2001-11-27)
The recent availability of specific inhibin assays has demonstrated that inhibin B is the relevant circulating inhibin form in the human male. Inhibin B is a dimer of an alpha and a betaB subunit. It is produced exclusively by the
PLoS neglected tropical diseases, 14(6), e0008335-e0008335 (2020-06-09)
Zika virus (ZIKV), a neglected tropical disease until its re-emergence in 2007, causes microcephaly in infants and Guillain-Barré syndrome in adults. Its re-emergence and spread to more than 80 countries led the World Health Organization in 2016 to declare a
British journal of cancer, 100(10), 1534-1539 (2009-04-23)
Large chromosomal regions can be suppressed in cancer cells as denoted by hypermethylation of neighbouring CpG islands and downregulation of most genes within the region. We have analysed the extent and prevalence of long-range epigenetic silencing at 2q14.2 (the first
Proceedings of the National Academy of Sciences of the United States of America, 113(7), 1829-1834 (2016-02-03)
Spermatogonial stem cells (SSCs) are a subpopulation of undifferentiated spermatogonia located in a niche at the base of the seminiferous epithelium delimited by Sertoli cells and peritubular myoid (PM) cells. SSCs self-renew or differentiate into spermatogonia that proliferate to give
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