所有图片(1)
About This Item
经验公式（希尔记法）:
C21H23FN2O3 · HCl
分子量:
406.88
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
推荐产品
形狀
solid
品質等級
溶解度
H2O: ≤0.5 mg/mL
起源
Roche
儲存溫度
2-8°C
SMILES 字串
Cl.NC(=O)c1ccc(OCCC(O)N2CCC(=CC2)c3ccc(F)cc3)cc1
InChI
1S/C21H23FN2O3.ClH/c22-18-5-1-15(2-6-18)16-9-12-24(13-10-16)20(25)11-14-27-19-7-3-17(4-8-19)21(23)26;/h1-9,20,25H,10-14H2,(H2,23,26);1H
InChI 密鑰
NYFXHCMXYODFLP-UHFFFAOYSA-N
基因資訊
human ... GRIN2B(2904)
生化／生理作用
NR2B-selective, noncompetitive NMDA glutamate receptor antagonist
特點和優勢
This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
Neuronal nicotinic acetylcholine receptors as novel drug targets.
G K Lloyd et al.
The Journal of pharmacology and experimental therapeutics, 292(2), 461-467 (2000-01-20)
Shuai Huang et al.
Molecular plant, 9(12), 1620-1633 (2016-10-21)
Nucleotide-binding leucine-rich repeat (NLR) proteins serve as immune receptors in both plants and animals. To identify components required for NLR-mediated immunity, we designed and carried out a chemical genetics screen to search for small molecules that can alter immune responses
Ghelardini, C., et al.
Drug Development Research, 40, 251-258 (1997)
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