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Merck

R1276

Sigma-Aldrich

Reversin 121

≥97% (HPLC), powder

别名:

Boc-Asp(Obzl)-Lys(Z)-OtBu

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About This Item

经验公式(希尔记法):
C34H47N3O9
分子量:
641.75
MDL號碼:
分類程式碼代碼:
12161501
PubChem物質ID:
NACRES:
NA.47

化驗

≥97% (HPLC)

形狀

powder

顏色

white

mp

200 °C

溶解度

DMSO or ethanol: soluble

儲存溫度

−20°C

SMILES 字串

CC(C)(C)OC(=O)N[C@@H](CC(=O)OCc1ccccc1)C(=O)N[C@@H](CCCCNC(=O)OCc2ccccc2)C(=O)OC(C)(C)C

InChI

1S/C34H47N3O9/c1-33(2,3)45-30(40)26(19-13-14-20-35-31(41)44-23-25-17-11-8-12-18-25)36-29(39)27(37-32(42)46-34(4,5)6)21-28(38)43-22-24-15-9-7-10-16-24/h7-12,15-18,26-27H,13-14,19-23H2,1-6H3,(H,35,41)(H,36,39)(H,37,42)/t26-,27-/m0/s1

InChI 密鑰

SVNKEDMVAQBLLN-SVBPBHIXSA-N

基因資訊

human ... GRIN2A(2903)
mouse ... GRIN2A(14811)
rat ... GRIN2A(24409)

一般說明

Reversin 121 is an analog of reversin and a dipeptide derivative.

應用

Reversin 121 has been used to determine the activity of P-glycoprotein in human retinal pigment epithelium.

生化/生理作用

Peptide chemosensitizer, inhibitor of P-glycoprotein.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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P-glycoprotein expression in human retinal pigment epithelium
Brain GK, et al.
Molecular Vision (2002)
Michelle Prudhomme
Advances in Anticancer Agents in Medicinal Chemistry, 1 (2013)

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