PRS2325

Anti-CASPASE-12 (ab1) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 别名: Anti-Casp-12
• MDL號碼: MFCD03454856
• 分類程式碼代碼: 12352203
• NACRES: NA.41

属性

• 生物源: rabbit
• 品質等級: 100
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: predicted mol wt 46 kDa
• 物種活性: rat, mouse, human
• 技術: immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• UniProt登錄號: O08736
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: mouse ... Casp12(12364)

说明

一般說明

Caspase 12 (CASP12), a member of the caspase family, is expressed in the Golgi complex.

免疫原

a peptide corresponding to amino acids 2-17 of murine caspase-12.

應用

Anti-CASPASE-12 (ab1) antibody produced in rabbit has been used in western blotting.

生化／生理作用

Murine caspase 12 (CASP12) is activated during endoplasmic reticulum stress and activates other caspases which act on substrates, ultimately leading to apoptosis. The protein has been shown to be activated during progression of retinal degeneration in animal models. In mice models, CASP12 has been shown to cause neuronal death resulting from ischemia/reperfusion.

聯結

The action of this antibody can be blocked using blocking peptide SBP2325.

外觀

Solution in phosphate buffered saline containing 0.02% sodium azide

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable