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PLA0264

Sigma-Aldrich

Rabbit anti-Ku80 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

别名:

80kDa, 86 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 80 kDa subunit, CTC box-binding factor 85 kDa subunit, CTC85, CTCBF, DNA repair protein XRCC5, KARP-1, KARP1, KU80, KUB2, Ku autoantigen, Ku86, NFIV, TLAA, X-ray repair complementing defective repair in Chinese hamster cells 5, double-strand-break rejoining, lupus Ku autoantigen protein p86, nuclear factor IV, thyroid-lupus autoantigen

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity purified immunoglobulin

抗體產品種類

primary antibodies

等級

Powered by Bethyl Laboratories, Inc.

物種活性

human

技術

immunohistochemistry: 1:100- 1:500
immunoprecipitation (IP): 2-5 μg/mg
western blot: 1:2,000- 1:10,000

登錄號

NP_066964.1

運輸包裝

wet ice

儲存溫度

2-8°C

目標翻譯後修改

unmodified

基因資訊

rabbit ... Ku80(7520)

免疫原

The epitope recognized by PLA0264 maps to a region between residue 150 and 200 of human Lupus Ku autoantigen protein p86 using the numbering given in entry NP_066964.1 (GeneID 7520).

外觀

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

其他說明

Ku80 is the 80 kDa subunit of the lupus Ku autoantigen. The lupus Ku autoantigen was identified in individuals with systemic lupus erythematosus (SLE) and related disorders. The Ku antigen is a heterodimer of Ku70 and Ku80. The Ku70/Ku80 complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P13010].

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Dan Wang et al.
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Despite recent advances in our understanding of the function of long noncoding RNAs (lncRNAs), their roles and functions in DNA repair pathways remain poorly understood. By screening a panel of uncharacterized lncRNAs to identify those whose transcription is induced by
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Treatment of central nervous system (CNS) malignancies typically involves radiotherapy to forestall tumor growth and recurrence following surgical resection. Despite the many benefits of cranial radiotherapy, survivors often suffer from a wide range of debilitating and progressive cognitive deficits. Thus

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