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Merck

PHG0001

SAFC

HEPES

制药生产

别名:

4-(2-羟乙基)哌嗪-1-乙磺酸, N-(2-羟乙基)哌嗪-N′-(2-乙磺酸)

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About This Item

经验公式(希尔记法):
C8H18N2O4S
CAS号:
分子量:
238.30
Beilstein:
883043
EC號碼:
MDL號碼:
分類程式碼代碼:
12161700
NACRES:
NA.21

生物源

synthetic

品質等級

形狀

powder

技術

cell culture | mammalian: suitable

雜質

Endotoxin, microbial, and trace metals; tested

pH值

4.7-5.3 (, )

有用的pH值範圍

6.8-8.2

pKa (25 °C)

7.5

適合性

suitable for manufacturing use

異物活動

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

SMILES 字串

OCCN1CCN(CC1)CCS(O)(=O)=O

InChI

1S/C8H18N2O4S/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14/h11H,1-8H2,(H,12,13,14)

InChI 密鑰

JKMHFZQWWAIEOD-UHFFFAOYSA-N

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一般說明

我们用于生物制药加工的SAFC®系列优质原料经过严格的质量控制流程,配合记录文件和技术专长帮助我们的客户达到M-Clarity 计划规定的要求

M-Clarity 计划

缓冲液质量是生物制药工艺成功的关键,因为缓冲液几乎在每一个生产步骤中都是必不可少的。

我们广泛的缓冲材料产品线经过妥善管控,可根据您的需求量身定制。从低风险应用的非 GMP 等级,到高风险应用的 IPEC-PQG GMP标准,我们的产品可满足您的所有制造需求。

應用

HEPES是一种生物缓冲液,通常被称为“好”缓冲液。它是最常用的生物缓冲液,因为HEPES的pKa为7.31,与生理pH值7.36相对应。HEPES被认为是对培养细胞系无毒的一种物质,高度可溶于水并可为溶液提供高澄清度。

HEPES用于细胞培养基、生物制药缓冲制剂(上游和下游)以及诊断试剂。基于HEPES的缓冲液被用于纯化抗体、生物活性物质、蛋白质和生长因子的生物过程。

法律資訊

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

取代透過

产品编号
说明
价格

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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