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Merck

P6656

Sigma-Aldrich

普马嗪 盐酸盐

别名:

10-(3-二甲基氨丙基)吩噻嗪 盐酸盐

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About This Item

线性分子式:
C17H20N2S · HCl
CAS号:
分子量:
320.88
Beilstein:
3753230
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.77

形狀

solid

起源

Baxter

儲存溫度

2-8°C

SMILES 字串

Cl[H].CN(C)CCCN1c2ccccc2Sc3ccccc13

InChI

1S/C17H20N2S.ClH/c1-18(2)12-7-13-19-14-8-3-5-10-16(14)20-17-11-6-4-9-15(17)19;/h3-6,8-11H,7,12-13H2,1-2H3;1H

InChI 密鑰

JIVSXRLRGOICGA-UHFFFAOYSA-N

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一般說明

Promazine hydrochloride (PMZ) belongs to the phenothiazine drug family. Promazine is a D2 dopamine receptor antagonist and has antipsychotic and anticholinergic functionality. It is used for pain management and is also used for treating hypersensitivity reactions.

應用

Promazine hydrochloride has been used in conductivity and surface tension measurements and for testing inhibition of feline coronavirus (FCoV) in Felis catus whole fetus-4 (fcwf-4) cells.

生化/生理作用

D2 dopamine receptor antagonist; phenothiazine antipsychotic.

特點和優勢

This compound was developed by Baxter. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral - Skin Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Study of the interaction between promazine hydrochloride and surfactant (conventional/gemini) mixtures at different temperatures.
Rub MA, et al.
Journal of Solution Chemistry, 43(5), 930-949 (2014)
Promazine in the treatment of delusional parasitosis.
Cubala W, et al.
Psychiatria Danubina, 23(2.), 198-199 (2011)
Determination of thiazinamium, promazine and promethazine in pharmaceutical formulations using a CZE method.
Lara FJ, et al.
Analytica Chimica Acta, 535(1-2), 101-108 (2005)
Synergistic antiviral effect of Galanthus nivalis agglutinin and nelfinavir against feline coronavirus.
Hsieh LE, et al.
Antiviral Research, 88(1), 25-30 (2010)
W A Daniel et al.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 9(4), 337-344 (1999-07-28)
The aim of the present study was to investigate a possible impact of the three selective serotonin reuptake inhibitors (SSRIs) fluoxetine, fluvoxamine and sertraline on the pharmacokinetics of promazine in a steady state in rats. Promazine was administered twice a

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