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Merck

P2517

Sigma-Aldrich

L-α-磷脂酰肌醇 铵盐 溶液 来源于牛肝脏

10 mg/mL in chloroform, ≥98% (TLC)

别名:

1,2-二酰基-sn-甘油-3-磷酸基-(1-D-myo-肌醇), PI, PtdIns

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About This Item

分類程式碼代碼:
12352200
NACRES:
NA.77

品質等級

化驗

≥98% (TLC)

濃度

10 mg/mL in chloroform

儲存溫度

−20°C

生化/生理作用

Phosphatidylinositol is a phosphoglyceride, containing inositol as a cyclohexanol head group. The phosphatidylinositol signaling pathway is also called as double signaling pathway as it generates two secondary messengers. It is associated with a number of physiological processes in plants. This includes the development of pollen and vascular organs, root and root hair growth, hormone response and stress tolerance.
磷脂膜组分,磷酸肌醇的前体。

特點和優勢

This compound is featured on the Phosphoinositide Kinases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

其他說明

主要含硬脂酸和花生四烯酸。

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

標靶器官

Central nervous system

儲存類別代碼

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


分析证书(COA)

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Cell Biology, 471-471 (2007)
S J Heydrick et al.
The Journal of clinical investigation, 91(4), 1358-1366 (1993-04-01)
Activation of phosphatidylinositol-3-kinase (PI3K) is one of the earliest postreceptor events in the insulin signaling pathway. Incubation of soleus muscles from lean mice with 50 nM insulin caused a 3-10-fold increase in antiphosphotyrosine-immunoprecipitable PI3K (antiPTyr-PI3K) activity within 2 min in
Sarah J Tilley et al.
Structure (London, England : 1993), 12(2), 317-326 (2004-02-14)
Phosphatidylinositol transfer protein alpha (PITPalpha) selectively transports and promotes exchange of phosphatidylinositol (PI) and phosphatidylcholine (PC) between lipid bilayers. In higher eukaryotes PITPalpha is required for cellular functions such as phospholipase C-mediated signaling, regulated exocytosis, and secretory vesicle formation. We
Functional Characterization of Arabidopsis Phosphatidylinositol Monophosphate 5-kinase 2 in Lateral Root Development, Gravitropism and Salt Tolerance, 2-2 (2014)
L Raptis et al.
Journal of virology, 63(2), 753-758 (1989-02-01)
Polyomavirus middle tumor antigen (mT) was expressed in a line of mouse NIH 3T3 cells under control of the dexamethasone-regulatable mouse mammary tumor virus promotor. Contrary to rat F111 cells which were rendered anchorage independent by mT expression alone (L.

实验方案

(soybean), ≥97%; L-α-Phosphatidylethanolamine from egg yolk, Type III, ≥97% (TLC), lyophilized powder; L-α-Phosphatidylcholine, from egg yolk, Type XVI-E, ≥99% (TLC), lyophilized powder; Sphingomyelin, from chicken egg yolk, ≥95%

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