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應用
乳清酸（OA）是从头嘧啶生物合成的中间体，可用于研究乳清酸磷酸核糖基转移酶（OPRT）的特异性和动力学，其催化从 5′-磷酸-α-d-核糖 1′-二磷酸（PRPP）到乳清酸（OA）的可逆磷酸核糖转移，形成焦磷酸盐和乳清酸 5′-单磷酸（OMP）。乳清酸用作通过产氨棒杆菌（ATCC 6872）或酿酒酵母等微生物潜在的商业生物生产尿苷 5′-单磷酸（UMP）的原料。乳清酸可用于研究 AMPK/SREBP-1 依赖性细胞信号传导途径,以及研究诱导肝脏脂肪生成的转录调节机制。
訊號詞
Warning
危險分類
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
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European journal of medicinal chemistry, 45(12), 5899-5909 (2010-10-23)
The enzyme dihydroorotate dehydrogenase (DHODH) has been suggested as a promising target for the design of trypanocidal agents. We report here the discovery of novel inhibitors of Trypanosoma cruzi DHODH identified by a combination of virtual screening and ITC methods.
David Pérez-Pascual et al.
Frontiers in microbiology, 8, 2168-2168 (2017-11-23)
A fascinating characteristic of most members of the genus
Thomas D Loan et al.
New biotechnology, 49, 104-111 (2018-10-23)
Nucleoside triphosphates (NTPs) are important synthetic targets with diverse applications in therapeutics and diagnostics. Enzymatic routes to NTPs from simple building blocks are attractive, however the cost and complexity of assembling the requisite mixtures of multiple enzymes hinders application. Here
Monika Feigenbutz et al.
PloS one, 8(11), e80752-e80752 (2013-11-14)
Rrp6 is a conserved catalytic subunit of the eukaryotic nuclear exosome ribonuclease complex that functions in the productive 3' end maturation of stable RNAs, the degradation of transiently expressed noncoding transcripts and in discard pathways that eradicate the cell of
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