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![硝酸还原酶 (NAD[P]H) 来源于黑曲霉 lyophilized powder, ≥300 units/g solid](/deepweb/assets/sigmaaldrich/product/images/309/282/2a67ae4d-ca55-4f0b-96ec-34748ff8a21e/640/2a67ae4d-ca55-4f0b-96ec-34748ff8a21e.jpg)
重組細胞
expressed in E. coli
品質等級
化驗
≥90% (SDS-PAGE)
形狀
lyophilized powder
比活性
≥100 units/mL
分子量
monomer 24000
環保替代產品特色
Waste Prevention
Safer Solvents and Auxiliaries
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
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環保替代類別
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
Escherichia coli K12 ... nfsB(945483)
相关类别
一般說明
硝基还原酶是一种黄素蛋白，由NfsB基因编码。它包含一个二聚体，每个亚基具有217个氨基酸和活性位点。该结构具有FMN和与酶结合的底物。
應用
大肠杆菌来源硝基还原酶可结合猪肝酯酶(PLE)用于偶联结合反应。它还还可结合探针HyCL-3和HyCL-4-AM针对大鼠肝微粒体进行化学发光响应研究。
生化／生理作用
硝基还原酶(NTR)可催化还原硝基芳香族底物和醌。NTR的F124K突变体可用于癌症治疗，改善药物CB1954的敏化作用。
硝基还原酶在NADPH或NADH为还原剂的氧还系统中有重要作用。
硝基还原酶增强了生命体对于含氮药物，比如甲硝唑的敏感度，它将氮基团转化为有毒的氮自由基。
能够还原奎宁。 该酶可以激活抗体引导酶前药治疗的前药。
物理性質
含有PBS的冻干粉。 作为辅药不含有BSA
單位定義
在pH7.4、37℃、存在甲萘醌和NADH的条件下，一单位酶每分钟能够还原1μmole细胞色素C。
準備報告
使用没有动物组分的材料生产。
儲存類別代碼
13 - Non Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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