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生物源
bovine
品質等級
形狀
lyophilized powder
技術
immunoblotting: suitable
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
bovine ... ALB(280717)
一般說明
Albumin, Nitrated (Nitrated BSA), is prepared by chemical modification of bovine serum albumin (BSA) by peroxynitrite. Peroxynitrite (ONOO-), a potent oxidant is an important member of the family of reactive oxygen and nitrogen species.
應用
Positive control in immunoblotting assays for Anti-Nitrotyrosine (Sigma Product Number N 0409).
生化／生理作用
Peroxynitrite promotes the nitration of tyrosine residues in proteins linked, oxidation of redox metal centers, DNA, lipids and nitrosation of cysteine residues in proteins, suggesting that peroxynitrite plays a major role in oxidative cellular damage. Peroxynitrite has been implicated in the pathogenesis of several inflammatory, infectious and degenerative human disease. These include neurological conditions such as Alzheimer′s disease, amyotrophic lateral sclerosis (ALS), the pathogenesis of asthma, atherosclerosis, and a variety of conditions precipitated by endothelial injury.
外觀
Lyophilized from 0.01 M phosphate buffered saline, pH 7.4
準備報告
Bovine serum albumin (BSA) nitrated with peroxynitrite.
分析報告
Does not contain sodium azide
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Inhibitory effect of isoflavones on peroxynitrite-mediated low-density lipoprotein oxidation
Lai H and Yen GC
Bioscience, Biotechnology, and Biochemistry, 66(1), 22-28 (2002)
The Intracellular Redox Stress Caused by Hexavalent Chromium is Selective for Proteins that Have Key Roles in Cell Survival and Thiol Redox Control
Judith M
Toxicology (2011)
Nitric oxide and peroxynitrite in health and disease
Pacher P, et al.
Physiological Reviews, 87(1), 315-424 (2007)
Péter Borbély et al.
Antioxidants (Basel, Switzerland), 10(1) (2021-01-13)
Selenium (Se) enrichment of Stevia rebaudiana Bertoni can serve a dual purpose, on the one hand to increase plant biomass and stress tolerance and on the other hand to produce Se fortified plant-based food. Foliar Se spraying (0, 6, 8
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