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一般說明
NGF-β基因定位于人类染色体1p13.2。
重组人β-NGF在人293细胞中以120个氨基酸的同型二聚体(非二硫键)表达,计算分子量为13.5 kDa(单体)。神经生长因子β(β-NGF)是一种在结构上与BDNF、NT-3和NT-4相关的神经营养因子。天然β-NGF的产生发生在上皮细胞和脑下垂体中。
生化/生理作用
NGF-β基因的突变与疼痛感的丧失有关。
神经生长因子β(β-NGF)是一种有效的神经营养因子,通过其受体β-NGFR发出信号,在感觉和交感神经系统的发育和保存中起着至关重要的作用。β-NGF促进基底前脑胆碱能神经元的存活和胆碱能表型,并在体外刺激胚胎三叉神经运动神经元的神经突向外生长。
注意
产品在供应时可保持至少2年的活性。 初始解冻后,建议将蛋白以工作等分试样储存在-20℃下。
外觀
该产品从PBS中冻干获得。
準備報告
打开前短暂离心小瓶。 建议在含有0.1%无内毒素重组人血清白蛋白的无菌DDW中复溶蛋白质,使其最终浓度为100 μg/mL。
儲存和穩定性
将产品储存在-20°C下。产品在供应时可保持至少2年的活性。初始解冻后,建议将蛋白以工作等分试样储存在-20 °C下。
分析報告
通过人TF-1细胞(人红白血病指示细胞系)增殖的剂量依赖性刺激测定比活性。
免責聲明
除非我们的目录中另有说明,否则我们的产品预期仅用于研究用途,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或对人类或动物的任何类型的消费或应用。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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