N4267

Neurokinin A

≥97% (HPLC)

• 别名: α-神经激肽
• 线性分子式: C₅₀H₇₉N₁₃O₁₅S
• CAS号: 86933-74-6
• 分子量: 1133.32
• MDL號碼: MFCD00167560
• 分類程式碼代碼: 51111800
• PubChem物質ID: 24897700
• NACRES: NA.32

属性

• 品質等級: 200
• 化驗: ≥97% (HPLC)
• 形狀: powder
• 成份: Peptide content, ≥70%
• UniProt登錄號: P20366
• 儲存溫度: −20°C
• SMILES 字串: CSCCC(NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)C(CO)NC(=O)C(CC(O)=O)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(N)Cc2cnc[nH]2)C(C)O)C(C)C)C(N)=O
• InChI: 1S/C50H80N14O14S/c1-26(2)18-34(45(73)58-32(42(53)70)15-17-79-6)57-38(67)23-55-49(77)40(27(3)4)63-47(75)35(19-29-12-8-7-9-13-29)60-48(76)37(24-65)62-46(74)36(21-39(68)69)61-50(78)41(28(5)66)64-44(72)33(14-10-11-16-51)59-43(71)31(52)20-30-22-54-25-56-30/h7-9,12-13,22,25-28,31-37,40-41,65-66H,10-11,14-21,23-24,51-52H2,1-6H3,(H2,53,70)(H,54,56)(H,55,77)(H,57,67)(H,58,73)(H,59,71)(H,60,76)(H,61,78)(H,62,74)(H,63,75)(H,64,72)(H,68,69)
• InChI 密鑰: HEAUFJZALFKPBA-UHFFFAOYSA-N
• 基因資訊: human ... TAC1(6863)

说明

Amino Acid Sequence

His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2

一般說明

Neurokinin A is an 11 amino acid peptide. It is a member of tachykinin family, which includes neurokinin A, neurokinin B, neuropeptide K, neuropeptide Y and hemokinin-1. The gene encoding neurokinin A is localized on human chromosome 7q21.3.

生化／生理作用

Neurokinin A improves the multiplication and paracrine ability of stem cells acquired from adipose in vitro. It participates in the movement of several organ tracts, triggers glandular secretion and controls autonomic reflexes. Neurokinin A plays an important role in neuroimmune and systemic autoimmune/inflammatory conditions like multiple sclerosis (MS), rheumatoid arthritis, inflammatory bowel disease and also in infections and cancer.

其他說明

Lyophilized from 0.1% TFA in H2O

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)