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Merck

MAK530

Sigma-Aldrich

Alkaline Phosphatase (ALP) Assay Kit

sufficient for 100 fluorometric tests

别名:

Fluorometric Alkaline Phosphatase Assay Kit

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About This Item

分類程式碼代碼:
12161503
NACRES:
NA.84

品質等級

應用

pharmaceutical

檢測方法

fluorometric

相關疾病

cancer; neurological disorders; gastrointestinal diseases; genitourinary disorders

運輸包裝

wet ice

儲存溫度

−20°C

一般說明

Alkaline phosphatase (ALP) catalyzes the hydrolysis of phosphate esters in an alkaline environment, resulting in the formation of an organic radical and inorganic phosphate. In mammals, this enzyme is found mainly in the liver and bones. Marked increase in serum ALP levels, a disease known as hyperalkalinephosphatasemia, has been associated with malignant biliary obstruction, primary biliary cirrhosis, primary sclerosing cholangitis, hepatic lymphoma and sarcoidosis.

特點和優勢

  • Detection limit of 0.02 U/L
  • Compatible with high-throughput handling systems.

適合性

The kit is suitable for ALP activity in serum, plasma and other sources, characterization and quality control for ALP production, and for high-throughput screening for ALP modulators.

原則

The Alkaline Phosphatase (ALP) Assay Kit utilizes 4-methylumbelliferyl phosphate that is hydrolyzed by ALP into the highly fluorescent product 4methylumbelliferone. The rate of the fluorescence increase is directly proportional to the enzyme activity.

象形圖

Corrosion

訊號詞

Danger

危險聲明

危險分類

Eye Dam. 1

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


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