MAK325

Cholesterol Uptake Assay Kit

sufficient for 100 fluorometric tests

• 分類程式碼代碼: 12161503
• NACRES: NA.84

属性

• 用途: sufficient for 100 fluorometric tests
• 檢測方法: fluorometric
• 相關疾病: obesity; cardiovascular diseases; cancer
• 儲存溫度: −20°C

说明

一般說明

Cholesterol, a crucial sterol and lipid component, is present in cell membranes and circulates in the bloodstream of all animals. It plays essential roles in maintaining cell membrane structure, hormone synthesis, and facilitating cell signaling processes. The intricate regulation of cellular cholesterol levels is paramount, as imbalances have been linked to conditions such as obesity and heart disease. Moreover, heightened cholesterol uptake has been correlated with the rapid proliferation of cancer cells. Through monitoring cellular cholesterol uptake, researchers can delve into these pressing health concerns, advancing both drug discovery efforts and biochemical research aimed at identifying potential treatment modalities.

應用

The Cholesterol Uptake Assay Kit may be used for:

• Drug Discovery
• Cardiovascular Research
• Obesity Research
• Cancer Research

特點和優勢

• Simplified Process: Experience a streamlined procedure as cell treatment occurs directly in the fluorescence 96-well plate, saving time and effort.
• High-Throughput Compatibility: Seamlessly integrate the kit into high-throughput handling systems for enhanced efficiency and accuracy.

適合性

Suitable for testing cholesterol uptake by adherent cells, screening of
cholesterol uptake inhibitors, and evaluation of effect of drugs on
cholesterol uptake.

原則

The cholesterol uptake assay kit is based on cellular uptake of a fluorescently tagged cholesterol probe. The fluorescence intensity measured at λex/em = 485/535 nm is proportional to the amount of cholesterol uptaken by the cells.

其他說明

For additional information on our range of Biochemicals, please complete this form.

安全信息

• 象形圖: GHS02,GHS08,GHS07
• 訊號詞: Danger
• 危險聲明: H225,H319,H336,H371
• 防範說明: P210 - P233 - P240 - P241 - P305 + P351 + P338 - P308 + P311
• 危險分類: Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 2 - STOT SE 3
• 標靶器官: Central nervous system, Eyes,Central nervous system
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 1