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Merck

M8816

Sigma-Aldrich

来自肝脏的微粒体,合并

from Monkey(Cynomolgus spp.), male

别名:

lab equipment accessory

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About This Item

分類程式碼代碼:
12161501
NACRES:
NB.35

生物源

Monkey (Cynomolgus spp.)

形狀

liquid

比活性

≥5000 units/mg protein

包裝

vial of ~10 mg

運輸包裝

dry ice

儲存溫度

−70°C

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應用

Microsomes from Liver, Pooled has been used to measure the in vitro stabilities of the prodrugs. It has also been used in microsomal incubation to generate BTX-3 metabolites to serve as references for liquid chromatography with tandem mass spectrometry (LC-MS/MS) analyses of urine.

生化/生理作用

肝微粒体是来源于肝细胞内质网的亚细胞颗粒。这些微粒体是药物代谢酶(包括细胞色素 P-450)的丰富来源。不同来源的微粒体池有助于研究外源代谢和药物相互作用。
Microsomal cytochrome P450 proteins can catalyze the transfer of a single oxygen atom to endogenous and exogenous compounds, like steroids and phenobarbital, meant for excretion and detoxification.

單位定義

One unit will produce 1.0 picomole of 6 beta-hydroxytestosterone per minute at pH 7.4 at 37 deg C.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Ann Abraham et al.
Toxicon : official journal of the International Society on Toxinology, 52(2), 237-245 (2008-06-28)
Urine specimens from patients diagnosed with neurotoxic shellfish poisoning (NSP) were examined for biomarkers of brevetoxin intoxication. Brevetoxins were concentrated from urine by using solid-phase extraction (SPE), and analyzed by enzyme-linked immunosorbent assay (ELISA) and liquid chromatography-tandem mass spectrometry (LC-MS/MS).
Biochemistry and cell biology
The Cytokine Handbook (2016)

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