所有图片(1)
About This Item
经验公式（希尔记法）:
C10H15N3O5
CAS号:
分子量:
257.24
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
推荐产品
化驗
≥95% (HPLC)
形狀
powder
儲存條件
desiccated
顏色
white to off-white
溶解度
H2O: >20 mg/mL
儲存溫度
−20°C
SMILES 字串
C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1N2C=CC(N)=NC2=O
InChI
1S/C10H15N3O5/c1-10(17)7(15)5(4-14)18-8(10)13-3-2-6(11)12-9(13)16/h2-3,5,7-8,14-15,17H,4H2,1H3,(H2,11,12,16)/t5-,7-,8-,10-/m1/s1
InChI 密鑰
PPUDLEUZKVJXSZ-VPCXQMTMSA-N
生化／生理作用
2′-C-Methylcytidine is a potent inhibitor of the HCV NS5B RNA polymerase. 2′-C-Methylcytidine was the first nucleoside NS5B inhibitor that showed clinical efficacy. 2′-C-Methylcytidine was found to be effective against the 17D vaccine strain of yellow fever virus YFV in cell culture.
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
其他客户在看
Natalie E Netzler et al.
Antiviral research, 146, 65-75 (2017-08-02)
Viruses of the Caliciviridae cause significant and sometimes lethal diseases, however despite substantial research efforts, specific antivirals are lacking. Broad-spectrum antivirals could combat multiple viral pathogens, offering a rapid solution when no therapies exist. The RNA-dependent RNA polymerase (RdRp) is
Natalie E Netzler et al.
Antimicrobial agents and chemotherapy, 63(6) (2019-03-20)
Globally, hepatitis E virus (HEV) causes significant morbidity and mortality each year. Despite this burden, there are no specific antivirals available to treat HEV patients, and the only licensed vaccine is not available outside China. Ribavirin and alpha interferon are
Abhilasha Madhvi et al.
Scientific reports, 7(1), 5816-5816 (2017-07-21)
Hepatitis C virus (HCV) is a global pathogen and infects more than 185 million individuals worldwide. Although recent development of direct acting antivirals (DAA) has shown promise in HCV therapy, there is an urgent need for the development of more
Myungeun Lee et al.
Scientific reports, 7, 44676-44676 (2017-03-24)
Despite recent advances in curing chronic hepatitis C (CHC), the high economic burden to therapy, viral drug resistance, difficult to treat hepatitis C virus (HCV) genotypes and patient groups are still of concern. To address this unmet medical needs, we
Navaneethan Palanisamy et al.
Pathogens and global health, 112(4), 210-226 (2018-05-11)
Alkhumra hemorrhagic fever virus (AHFV), a relatively new member of the Flaviviruses, was discovered in Saudi Arabia 23 years ago. AHFV is classified in the tick-borne encephalitis virus serocomplex, along with the Kyasanur forest disease virus (KFDV) and tick-borne encephalitis
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