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Merck

M2172

Sigma-Aldrich

1-硫代甘油

BioXtra, ≥97%

别名:

α-单硫代甘油, α-硫代甘油, 3-巯基-1,2-丙二醇

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About This Item

线性分子式:
HSCH2CH(OH)CH2OH
CAS号:
分子量:
108.16
Beilstein:
1732046
EC號碼:
MDL號碼:
分類程式碼代碼:
12352211
PubChem物質ID:
NACRES:
NA.25

產品線

BioXtra

品質等級

化驗

≥97%

形狀

liquid

雜質

≤0.0005% Phosphorus (P)

燃燒殘留物

≤0.1%

折射率

n20/D 1.527 (lit.)

bp

118 °C/5 mmHg (lit.)

密度

1.25 g/mL at 25 °C (lit.)

正離子痕跡

Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.02%
Pb: ≤0.001%
Zn: ≤0.0005%

儲存溫度

2-8°C

SMILES 字串

OCC(O)CS

InChI

1S/C3H8O2S/c4-1-3(5)2-6/h3-6H,1-2H2

InChI 密鑰

PJUIMOJAAPLTRJ-UHFFFAOYSA-N

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一般說明

1-硫代甘油刺激需氧生长的大肠杆菌合成卟啉。在体外 原位 是甘油激酶活性的抑制剂。

應用

它已被用于一项研究中,以评估大肠杆菌的巯基敏感基因和启动子。

準備報告

本品在乙醇 (1 mL/mL,50%,v/v) 中可混溶,得到澄清、无色溶液。也可在水中混溶 (0.1 M)。

象形圖

Skull and crossbones

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Skin Irrit. 2 - Skin Sens. 1B

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

210.2 °F - closed cup

閃點(°C)

99 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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W K Seltzer et al.
Life sciences, 39(16), 1417-1424 (1986-10-20)
The infantile form of glycerol kinase (GK) deficiency (McKusick No. 30703) (1) is characterized by adrenal cortical insufficiency, adrenal hypoplasia and developmental delay. The underlying biochemical mechanism(s) responsible for the observed clinical presentations are undetermined. Pursuant to our examination of
G T Javor
Journal of bacteriology, 171(10), 5607-5613 (1989-10-01)
The effect of 1-thioglycerol on the expression of genes of Escherichia coli was investigated. Pulse-labeled proteins from aerobically growing, 1-thioglycerol-treated E. coli were separated by two-dimensional gel electrophoresis, and their radioactivities were compared with those of identical proteins from nontreated
G T Javor et al.
Journal of bacteriology, 170(7), 3291-3293 (1988-07-01)
Mu dX(lac) insertion mutants of Escherichia coli CSH50 in which the expression of the lacZ gene was sensitive to the presence of exogenous 1-thioglycerol or dithiothreitol were isolated. Both stimulatory and inhibitory mutants were found. The existence of several thiol-sensitive
P Tengvall et al.
Biomaterials, 17(10), 1001-1007 (1996-05-01)
Thiol-modified surfaces are chemically well defined and suited for surface biological model experiments and biomaterials research. 3-Mercapto-1,2-propanediol (mercaptoglycerol, MG), immobilized on gold, spontaneously binds immunoglobulins from human serum and activates the complement system. The surface-bound complement factors were detected by
Jonas Wetterö et al.
Biomaterials, 23(4), 981-991 (2002-01-17)
Since the realization of a complement activation capacity by artificial surfaces upon contact with blood, a common belief has evolved that charged nucleophilic surface groups such as amine (-NH2) and hydroxyl (-OH) react with and eventually bind to the internal

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