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Merck

M1818

Sigma-Aldrich

莫林酮 盐酸盐

≥98% (HPLC), solid

别名:

3-Ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-4H-indol-4-one hydrochloride

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About This Item

经验公式(希尔记法):
C16H24N2O2 · HCl
CAS号:
分子量:
312.83
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:

品質等級

化驗

≥98% (HPLC)

形狀

solid

顏色

off-white

溶解度

H2O: 19 mg/mL

起源

Endo

SMILES 字串

CCC1=C(C)NC2=C1C(C(CN3CCOCC3)CC2)=O.Cl

InChI

1S/C16H24N2O2.ClH/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18;/h12,17H,3-10H2,1-2H3;1H

InChI 密鑰

GQWNECFJGBQMBO-UHFFFAOYSA-N

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生化/生理作用

D2 dopamine receptor antagonist; MAO inhibitor.

特點和優勢

This compound was developed by Endo. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

防範說明

危險分類

Acute Tox. 3 Oral

儲存類別代碼

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Jon McClellan et al.
Journal of the American Academy of Child and Adolescent Psychiatry, 46(8), 969-978 (2007-08-02)
The Treatment of Early Onset Schizophrenia Spectrum Disorders Study is a publicly funded clinical trial designed to compare the therapeutic benefits, safety, and tolerability of risperidone, olanzapine, and molindone in youths with early-onset schizophrenia spectrum disorders. The rationale, design, and
Treatment of morbidly obese psychotic patients with molindone: three case reports.
Robert E McCue et al.
The Journal of clinical psychiatry, 70(11), 1606-1607 (2009-12-25)
R B Rosse et al.
Clinical neuropharmacology, 19(5), 444-450 (1996-10-01)
This preliminary investigation examined the therapeutic efficacy of two doses of oral D-cycloserine (5 and 15 mg p.o. b.i.d.) administered as an adjuvant to molindone (150 mg p.o. q.d.) in the treatment of schizophrenia. D-Cycloserine is an agonist at the
M Froimowitz et al.
Drug design and discovery, 15(2), 63-81 (1997-08-01)
This study is an attempt to incorporate the butyrophenones, an important class of nontricyclic antipsychotic drugs, into a previously proposed pharmacophore model of tricyclic dopamine D2 receptor antagonist ligands. Conformational energy calculations were performed using the MM3-92 program on spiperone
The voices go, but the song remains the same: how can we rescue cognition in early-onset schizophrenia?
Peter Bachman et al.
Journal of the American Academy of Child and Adolescent Psychiatry, 51(5), 464-466 (2012-04-25)

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