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Merck

M0905

Sigma-Aldrich

4-Methylumbelliferyl β-D-mannopyranoside

≥98% (TLC), powder

别名:

4-Methylumbelliferyl β-D-mannoside

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About This Item

经验公式(希尔记法):
C16H18O8
CAS号:
分子量:
338.31
MDL號碼:
分類程式碼代碼:
12352204
PubChem物質ID:
NACRES:
NA.32

product name

4-Methylumbelliferyl β-D-mannopyranoside, ≥98% (TLC)

化驗

≥98% (TLC)

形狀

powder

溶解度

pyridine: 10 mg/mL, clear, colorless to faintly yellow

儲存溫度

−20°C

SMILES 字串

CC1=CC(=O)Oc2cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)ccc12

InChI

1S/C16H18O8/c1-7-4-12(18)23-10-5-8(2-3-9(7)10)22-16-15(21)14(20)13(19)11(6-17)24-16/h2-5,11,13-17,19-21H,6H2,1H3/t11-,13-,14+,15+,16-/m1/s1

InChI 密鑰

YUDPTGPSBJVHCN-NZBFACKJSA-N

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應用

4-Methylumbelliferyl β-D-mannopyranoside has been used as a fluorogenic substrate for β -mannosidase in the enzyme assay of mice tissue extracts, in cell-free translation and midgut of Lutzomyia longipalpis.

生化/生理作用

4-Methylumbelliferyl β-D-mannopyranoside is a fluorescent ligand for concanavalin A and interacts with its carbohydrate binding region. It is also a fluorogenic substrate for β-mannosidase.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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B T Adams et al.
Chemical communications (Cambridge, England), 51(57), 11390-11393 (2015-06-19)
β-Glucocerebrosidase deficiency leads to Gaucher disease and is a potential marker of Parkinson's disease. We have identified N-octyl conduritol aziridine as a potent and specific covalent inactivator of GBA1 in living cells. This compound is a promising lead towards a
C S Moraes et al.
Journal of insect physiology, 58(8), 1136-1145 (2012-06-12)
The sandfly Lutzomyia longipalpis (Lutz and Neiva, 1912) is the main vector of American Visceral Leishmaniasis. In spite of its medical importance and several studies concerning adult digestive physiology, biochemistry and molecular biology, very few studies have been carried out
H E Auer et al.
International journal of peptide and protein research, 24(5), 462-471 (1984-11-01)
Properties characteristic of the structure and function of dimeric concanavalin A have been studied as a function of pH in the acid pH range using preparations comprising intact subunits or enriched in fragmented chains. For intact subunits, the glycogen binding
Binding of 4-methylumbelliferyl alpha-D-mannopyranoside to tetrameric and unmodified or derivatized dimeric concanavalin A: equilibrium studies
Loontiens FG, et al.
Biochemistry, 16(2), 159-166 (1977)
Alternative substrates for use in the detection of goats heterozygous for beta-mannosidosis.
P J Healy et al.
Research in veterinary science, 33(1), 73-75 (1982-07-01)

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