推荐产品
product name
4-Methylumbelliferyl β-D-mannopyranoside, ≥98% (TLC)
化驗
≥98% (TLC)
形狀
powder
溶解度
pyridine: 10 mg/mL, clear, colorless to faintly yellow
儲存溫度
−20°C
SMILES 字串
CC1=CC(=O)Oc2cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)ccc12
InChI
1S/C16H18O8/c1-7-4-12(18)23-10-5-8(2-3-9(7)10)22-16-15(21)14(20)13(19)11(6-17)24-16/h2-5,11,13-17,19-21H,6H2,1H3/t11-,13-,14+,15+,16-/m1/s1
InChI 密鑰
YUDPTGPSBJVHCN-NZBFACKJSA-N
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應用
4-Methylumbelliferyl β-D-mannopyranoside has been used as a fluorogenic substrate for β -mannosidase in the enzyme assay of mice tissue extracts, in cell-free translation and midgut of Lutzomyia longipalpis.
生化/生理作用
4-Methylumbelliferyl β-D-mannopyranoside is a fluorescent ligand for concanavalin A and interacts with its carbohydrate binding region. It is also a fluorogenic substrate for β-mannosidase.
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
Chemical communications (Cambridge, England), 51(57), 11390-11393 (2015-06-19)
β-Glucocerebrosidase deficiency leads to Gaucher disease and is a potential marker of Parkinson's disease. We have identified N-octyl conduritol aziridine as a potent and specific covalent inactivator of GBA1 in living cells. This compound is a promising lead towards a
Journal of insect physiology, 58(8), 1136-1145 (2012-06-12)
The sandfly Lutzomyia longipalpis (Lutz and Neiva, 1912) is the main vector of American Visceral Leishmaniasis. In spite of its medical importance and several studies concerning adult digestive physiology, biochemistry and molecular biology, very few studies have been carried out
International journal of peptide and protein research, 24(5), 462-471 (1984-11-01)
Properties characteristic of the structure and function of dimeric concanavalin A have been studied as a function of pH in the acid pH range using preparations comprising intact subunits or enriched in fragmented chains. For intact subunits, the glycogen binding
Binding of 4-methylumbelliferyl alpha-D-mannopyranoside to tetrameric and unmodified or derivatized dimeric concanavalin A: equilibrium studies
Biochemistry, 16(2), 159-166 (1977)
Alternative substrates for use in the detection of goats heterozygous for beta-mannosidosis.
Research in veterinary science, 33(1), 73-75 (1982-07-01)
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