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Merck

M076000

Sigma-Aldrich

Sulfur 42

别名:

Phenyl-3H-1,2,4-dithiazol-3-one

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About This Item

经验公式(希尔记法):
C8H5NOS2
CAS号:
分子量:
195.26
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.03

種類

for DNA synthesis

品質等級

產品線

Proligo Reagents

化驗

≥99.0% (reversed phase HPLC)

形狀

solid

包裝

pkg of 1 g M076000-1G
2 g of 2 g M076000-2G

雜質

≤0.1% water content (Karl Fischer)

顏色

faintly yellow to yellow

溶解度

acetonitrile: 0.1 M, clear

適合性

conforms to structure for H-NMR

儲存溫度

2-8°C

SMILES 字串

O=C1SSC(C2=CC=CC=C2)=N1

InChI

1S/C8H5NOS2/c10-8-9-7(11-12-8)6-4-2-1-3-5-6/h1-5H

InChI 密鑰

LKDWQHQNDDNHSC-UHFFFAOYSA-N

一般說明

Sulfur 42 is a sulfurization reagent.

應用

Sulfur 42 is suitable for use instead of an Oxidizer during the synthesis cycle to manufacture thioated oligonucleotides.

特點和優勢

  • Sulfur 42 is at least 4 times more reactive than Beaucage reagent or PADS
  • Crystalline powder
  • Odourless, no foul smell
  • Solubility in ACN up to 0.28M at (+10 °C); no need to applied a co-solvent like in DCM, THF
  • The solvent for the dissolution of the reagent should be dry (< 50 ppm) in order to minimize P=O impurities
  • Stable in ACN solution for at least 21 days
  • Recommended reaction time for the sulfurization in oligonucleotide synthesis for a 0.1M solution is 60 sec

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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