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化驗
≥98% (HPLC)
≥98% (TLC)
形狀
powder
溶解度
acetic acid: 49.00-51.00 mg/mL, clear, colorless to yellow
儲存溫度
2-8°C
SMILES 字串
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(NCc4ccco4)ncnc23
InChI
1S/C15H17N5O5/c21-5-9-11(22)12(23)15(25-9)20-7-19-10-13(17-6-18-14(10)20)16-4-8-2-1-3-24-8/h1-3,6-7,9,11-12,15,21-23H,4-5H2,(H,16,17,18)/t9-,11-,12-,15-/m1/s1
InChI 密鑰
CAGLGYNQQSIUGX-SDBHATRESA-N
基因資訊
rat ... Adora1(29290) , Adora2a(25369) , Adora3(25370)
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一般說明
Kinetin riboside is a ribosylated form of kinetin. It is a natural cytokinin plant hormone.
應用
Kinetin riboside may be used:
- to study its cytotoxic effects on plant and animal tumor cells
- to investigate its apoptotic effects in both cancer and immortalized cells
- to elucidate its influence on human prostate cell epithelial-mesenchymal transition in vitro
生化／生理作用
Kinetin riboside exhibits cytotoxic and antiproliferative activities. In addition, it also shows anticancer activity by inducing apoptosis in various types of cancers including myeloid leukemia cells, mouse melanoma B16F-10 cells, and plant tumor cells.
儲存類別代碼
13 - Non Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
Bernard Griffaut et al.
International journal of biological macromolecules, 34(4), 271-275 (2004-09-18)
The cytotoxicity of two plant hormone compounds, kinetin and kinetin riboside, was studied on tumour cells, by colony forming assay with increased amount of cytotoxic molecules. The concentration of inhibitor required to reduce cell growth to 50% was determined for
Dennison Trinh et al.
Journal of neurochemistry, 156(6), 715-752 (2021-02-23)
Mitochondria are essential for neuronal function. They produce ATP to meet energy demands, regulate homeostasis of ion levels such as calcium and regulate reactive oxygen species that cause oxidative cellular stress. Mitochondria have also been shown to regulate protein synthesis
Effects of kinetin riboside on proliferation and proapoptotic activities in human normal and cancer cell lines.
Dudzik P, Dulinska-Litewka J, Wyszko E, et al.
The Journal of Cell Biology, 112, 2115-2124 (2011)
Zhenfang Cheng et al.
Journal of separation science, 41(11), 2386-2392 (2018-02-24)
In this work, an easy, effective, and sensitive method based on graphene oxide@silica@magnetite composites as adsorbent of magnetic solid-phase extraction combined with liquid chromatography and tandem mass spectrometry, was established and validated for the trace analysis of cytokinins in different
Bo-Hwa Choi et al.
Cancer letters, 261(1), 37-45 (2007-12-29)
Here, we demonstrate that kinetin riboside (KR), a cytokinin analog, induces apoptosis in HeLa and mouse melanoma B16F-10 cells. KR disrupted the mitochondrial membrane potential and induced the release of cytochrome c and activation of caspase-3. Bad were upregulated while
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