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Merck

I5659

Sigma-Aldrich

艾地苯醌

≥98% (HPLC), powder

别名:

2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione

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About This Item

经验公式(希尔记法):
C19H30O5
CAS号:
分子量:
338.44
MDL號碼:
分類程式碼代碼:
12352204
PubChem物質ID:
NACRES:
NA.25

product name

艾地苯醌, ≥98% (HPLC)

化驗

≥98% (HPLC)

形狀

powder

溶解度

methanol: 50 mg/mL, clear to slightly hazy

儲存溫度

room temp

SMILES 字串

O=C(C(OC)=C1OC)C(CCCCCCCCCCO)=C(C)C1=O

InChI

1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3

InChI 密鑰

JGPMMRGNQUBGND-UHFFFAOYSA-N

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一般說明

艾地苯醌是一种短链苯醌类药物。

應用

艾地苯醌已用于:
  • 处理用于药物治疗测定的突变肌纤蛋白 (mMYOC)细胞
  • 验证 C2C12 二次细胞筛选测定
  • 处理肥胖小鼠,测试艾地苯醌和 CoQ10 是否直接结合过氧化物酶体增殖物激活受体(PPAR)LBD、His 标记的 PPAR αδ 和γ LBD。

生化/生理作用

艾地苯醌用于治疗患有 Leber′遗传性视神经病变 (LHON)的青少年和成人的视力障碍。它可用作抗氧化剂。它有助于保护心肌免于氧化应激。
一种短链辅酶 Q 类似物,可通过介导电子从 N2 转移到氧来增强超氧化物的形成。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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