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Merck
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主要文件

I1646

Sigma-Aldrich

IL-3 human

≥97% (HPLC and SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

别名:

hIL-3, IL-3

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About This Item

MDL號碼:
MFCD00147276
分類程式碼代碼:
12352202
NACRES:
NA.77

产品名称

白细胞介素-3 人, IL-3, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

生物源

human

品質等級

200

重組細胞

expressed in E. coli

化驗

≥97% (HPLC and SDS-PAGE)

形狀

lyophilized powder

效力

≤1.0 ng/mL ED50/EC50

品質

endotoxin tested

分子量

15 kDa

包裝

pkg of 10 and 50 μg

儲存條件

avoid repeated freeze/thaw cycles

技術

cell culture | mammalian: suitable

雜質

≤0.1 EU/μg

UniProt登錄號

P08700

儲存溫度

−20°C

基因資訊

human ... IL3(3562)

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相关类别

生化／生理作用

白介素3（IL-3）是一种多功能蛋白，起初被称为克隆形成单位刺激活性（CFU-SA），由活化的T淋巴细胞产生。IL-3在多能造血祖细胞的早期发育中可支持多谱系克隆的形成。IL-3已显示出可从琼脂悬浮的骨髓细胞诱导巨噬细胞、嗜中性粒细胞、肥大细胞和巨核细胞的克隆形成。IL-3也可与IL-2发生互作，以刺激T淋巴细胞的生长并诱导活化B细胞分泌IgG。IL-3的其他同义词包括泛特异性造血素、多克隆刺激因子、肥大细胞生长因子、爆发促进活性、组胺生成细胞刺激因子、P细胞刺激因子和WEHI-3因子。
白细胞介素3是由活化的T淋巴细胞产生的一种多功能蛋白。 IL-3在多能造血祖细胞的早期发育中可支持多谱系克隆的形成。IL-3还与IL-2相互作用，以刺激T淋巴细胞的生长并诱导活化B细胞分泌IgG。

外觀

无添加剂冻干。已经过0.2 μm滤器过滤。

分析報告

通过剂量依赖性刺激人TF-1细胞的增殖来测量生物活性。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SLCL6950
SLCK9617
SLCJ0407
SLCH0548
SLCD8353

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Interleukin Family (IL)

The Interleukins comprise a disparate group of cytokines and growth factors that are produced by and released from leukocytes. Interleukin-1β (1L-1β) is released primarily from stimulated macrophages and monocytes and plays a key role in inflammatory and immune responses and may induce anti-tumor immunity.

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