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Merck

H6875

Sigma-Aldrich

Hippuryl-L-phenylalanine

别名:

Hippuryl-Phe, N-Benzoyl-Gly-Phe

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About This Item

经验公式(希尔记法):
C18H18N2O4
CAS号:
分子量:
326.35
Beilstein:
2167818
EC號碼:
MDL號碼:
分類程式碼代碼:
12352204
PubChem物質ID:
NACRES:
NA.32

化驗

≥98% (TLC)

形狀

powder

溶解度

acetic acid: 50 mg/mL, clear, colorless

儲存溫度

−20°C

SMILES 字串

OC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c2ccccc2

InChI

1S/C18H18N2O4/c21-16(12-19-17(22)14-9-5-2-6-10-14)20-15(18(23)24)11-13-7-3-1-4-8-13/h1-10,15H,11-12H2,(H,19,22)(H,20,21)(H,23,24)/t15-/m0/s1

InChI 密鑰

CCLJGZGVIQBNDH-HNNXBMFYSA-N

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應用

Hippuryl-L-phenylalanine has been used as a substrate for screening carboxypeptidase activity in Trogoderma granarium, Bactrocera oleae Gmelin and Apodiphus amygdali.

生化/生理作用

Hippuryl-L-phenylalanine is a substrate for carboxypeptidase A enzyme.

基底

Substrate for carboxypeptidase A

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Digestion and protein metabolism of Trogoderma granarium (Coleoptera: Dermestidae) fed on different barley varieties
Mardani-Talaee M, et al.
Journal of Stored Products Research, 73(1-2), 37-41 (2017)
P W Tardioli et al.
Biotechnology progress, 19(2), 565-574 (2003-04-05)
This paper presents stable carboxypeptidase A (CPA)-glyoxyl derivatives, to be used in the controlled hydrolysis of proteins. They were produced after immobilizing-stabilizing CPA on cross-linked 6% agarose beads, activated with low and high concentrations of aldehyde groups, and different immobilization
M E Sander et al.
Biochemical and biophysical research communications, 132(2), 681-687 (1985-10-30)
Carboxypeptidase A was incubated at -60 degrees C with an excess of O-(trans-p-chlorocinnamoyl)-L-phenyllactate, O-(hippuryl)-glycolate or N-(hippuryl)-L-phenylalanine. After rapid denaturation with trichloracetic acid the precipitated protein was reduced with [3H]NaCNBH3. 3H Labeled enzyme was isolated by gel chromatography on Sephadex G-25.
Digestive proteolytic activity in Apodiphus amygdali Germar (Hemiptera: Pentatomidae): effect of endogenous inhibitors
Ramzi S and Zibaee A
Journal of Entomological and Acarological Research, 46(2), 35-41 (2014)
Product stabilization of the two forms of carboxypeptidase A from buffalo pancreas
Sud M and Dua RD
Journal of Biosciences, 9(1-2), 83-90 (1985)

实验方案

Objective: To standardize a procedure for the assay of Carboxypeptidase A

Objective: To standardize a procedure for the assay of Carboxypeptidase A

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