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Merck

H6010

Sigma-Aldrich

L -高胱氨酸

≥98% (HPLC)

别名:

L-4,4'-二硫双(2-氨基丁酸)

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About This Item

经验公式(希尔记法):
C8H16N2O4S2
CAS号:
分子量:
268.35
Beilstein:
1728583
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.26

product name

L -高胱氨酸, ≥98% (HPLC)

化驗

≥98% (HPLC)

形狀

powder

顏色

white to off-white

mp

281-284 °C (dec.) (lit.)

應用

cell analysis
peptide synthesis

SMILES 字串

N[C@@H](CCSSCC[C@H](N)C(O)=O)C(O)=O

InChI

1S/C8H16N2O4S2/c9-5(7(11)12)1-3-15-16-4-2-6(10)8(13)14/h5-6H,1-4,9-10H2,(H,11,12)(H,13,14)/t5-,6-/m0/s1

InChI 密鑰

ZTVZLYBCZNMWCF-WDSKDSINSA-N

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生化/生理作用

L-同型半胱氨酸是 L-高半胱氨酸:L-高胱氨酸对的氧化成员。同型半胱氨酸/同型半胱氨酸来源于蛋氨酸。同型半胱氨酸是一种促血栓形成因子、血管舒张损伤因子、促炎因子和内皮型网织红细胞应激诱导因子,可用于研究心血管疾病的发病机制。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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S Ramakrishnan et al.
Indian journal of biochemistry & biophysics, 43(5), 275-283 (2006-12-01)
The amino acid homocysteine (Hcy), formed from methionine has profound importance in health and diseases. In normal circumstances, it is converted to cysteine and partly remethylated to methionine with the help of vit B12 and folate. However, when normal metabolism
Camila Simioni Vanzin et al.
Molecular genetics and metabolism, 104(1-2), 112-117 (2011-07-12)
Homocystinuria is an inherited disorder biochemically characterized by high urinary excretion of homocystine and increased levels of homocysteine (Hcy) and methionine in biological fluids. Affected patients usually have a variety of clinical and pathologic manifestations. Previous experimental data have shown
Geoffrey P McDermott et al.
Analytical chemistry, 83(15), 6034-6039 (2011-07-08)
The quantification of low-molecular mass thiols and disulfides involved in cellular redox processes is hindered by oxidation or degradation of analytes during conventional sample preparation steps (including deproteinization and derivatization). Researchers therefore seek techniques that minimize sample handling and permit
J Perła-Kaján et al.
Amino acids, 32(4), 561-572 (2007-02-08)
Homocysteine, a non-protein amino acid, is an important risk factor for ischemic heart disease and stroke in humans. This review provides an overview of homocysteine influence on endothelium function as well as on protein metabolism with a special respect to
Karin J A Lievers et al.
Annals of clinical biochemistry, 40(Pt 1), 46-59 (2003-01-25)
Homocysteine, a sulphur amino acid, is a branch-point intermediate of methionine metabolism. It can be degraded in the transsulphuration pathway to cystathionine, or remethylated to methionine via the remethylation pathway. In both pathways, major genetic defects that cause enzyme deficiencies

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Inborn errors of metabolism are caused by changes in specific enzymatic reactions and hundreds of different such alterations, which affect about 1 of every 5000 newborns, have been characterized.

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