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Merck

GW22921

Sigma-Aldrich

Anti-ST8SIA1 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

chicken

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

human

技術

western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... ST8SIA1(6489)

相关类别

一般說明

The previously assigned protein identifier Q6PZN5 has been merged into Q92185. Full details can be found on the UniProt database.

免疫原

Immunogen Sequence: GI # 4506953, sequence 4-18
Synthetic peptide sequence of ST8 α-N-acetyl-neuraminide α-2,8-sialyltransferase 1.

應用

Anti-ST8SIA1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

α-N-acetylneuraminide α-2,8-sialyltransferase is an enzyme encoded by the ST8SIA1 gene in humans. It acts as an oligosialyltransferase in a cellular context. ST8SIA1 gene encodes a ganglioside synthase and is susceptibile to diseases. The gene is found to be associated with Multiple sclerosis (MS).

外觀

Solution in phosphate buffered saline containing 0.02% sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Sreeram V Ramagopalan et al.
Journal of neuroimmunology, 212(1-2), 142-144 (2009-05-12)
Multiple sclerosis (MS) is a complex trait with a significant genetic component. Recent work has implicated the ST8SIA1 gene, encoding a ganglioside synthase, in susceptibility to the disease, perhaps with a parent-of-origin effect. In this investigation of 1318 MS patients
Agata Steenackers et al.
Molecules (Basel, Switzerland), 17(8), 9559-9572 (2012-08-14)
Glycosphingolipids from the ganglio-series are usually classified in four series according to the presence of 0 to 3 sialic acid residues linked to lactosylceramide. The transfer of sialic acid is catalyzed in the Golgi apparatus by specific sialyltransferases that show

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