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Merck

GW21017

Sigma-Aldrich

Anti-Tenascin antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

别名:

Anti-Cytotactin, Anti-Neuronectin, Anti-Tenascin C (hexabrachion)

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

chicken

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

human

製造商/商標名

Genway 15-288-21017

技術

western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... TNC(3371)

免疫原

Immunogen Sequence: GI # 4504549, sequence 18-175
Recombinant tenascin C (hexabrachion)

應用

Anti-Tenascin antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200. It is also used for immunohistology.

生化/生理作用

Tenascin-C (TNC) is an extracellular matrix protein that is expressed at low levels in normal adult tissue but is highly expressed around many tumors including ovarian tumors. High levels are observed in many diseases like heart failure, thrombosis, atherosclerosis and cancer. It plays an indispensable role in tumor development. Expression of this gene is induced by growth factors as well as mechanical strain in fibroblast. It is up-regulated within glioma tissues and cultured glioma cell lines. TNC possesses a multi-modular structure with a variety of functional properties.

外觀

Solution in phosphate buffered saline containing 0.02% sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Yucal Wang et al.
Oncology research, 20(11), 509-516 (2013-09-26)
Osteosarcoma (OS) is a kind of malignancy wherein the tumor cells form malignant bone-like or bone tissue. Tenascin-C (TN-C), an important extracellular matrix (ECM) protein, plays an indispensable role in tumor development. However, its regulatory factors, expression, and function in
Nicole Brösicke et al.
Cell and tissue research, 354(2), 409-430 (2013-08-22)
The extracellular matrix (ECM) protein tenascin-C (TN-C) is upregulated within glioma tissues and cultured glioma cell lines. TN-C possesses a multi-modular structure and a variety of functional properties have been reported for its domains. We describe five novel monoclonal antibodies
D Tastekin et al.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 35(7), 6619-6625 (2014-04-04)
Tenascin-C (TNC) is a key molecule in tissue remodeling, and high levels are observed in many diseases, including heart failure, thrombosis, atherosclerosis, and cancer. High TNC expression by immunohistochemical analysis has been shown in invasive and metastasizing tissues from a
Tastekin Didem et al.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 35(7), 6777-6782 (2014-04-12)
Tenascin-C (TNC) is an extracellular matrix protein that is expressed at low levels in normal adult tissue but is highly expressed around many tumors including ovarian tumors. The objective of this study was to determine the clinical significance of the
Daniel J Gibson et al.
Investigative ophthalmology & visual science, 54(7), 4776-4781 (2013-06-27)
To determine the topographical location and time course of development of corneal haze in a phototherapeutic keratectomy model using slit lamp examination, macrophotography, quantitative image analysis, and immunofluorescence staining of corneal sections. Rabbit corneas were ablated with an excimer laser

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