推荐产品
生物源
chicken
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
物種活性
human
製造商／商標名
Genway 15-288-20074F
技術
indirect ELISA: suitable
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... CP(1356)
應用
Anti-Ceruloplasmin antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Western Blotting (1 paper)
生化／生理作用
Ceruloplasmin (or caeruloplasmin) is a ferroxidase enzyme encoded by the CP gene in humans. It is a ferroxidase present in the cerebrospinal fluid (CSF). CP is associated with promoting the function of integrin binding, signaling and cell adhesion. The CP level is correlated negatively and indirectly with inflammation as well as fibrosis stages in male patients with chronic hepatitis B (CHB). It decreases the nitric oxide bioavailability in blood and is associated with cardiovascular disease (CVD).
外觀
Solution in phosphate buffered saline containing 0.02% sodium azide.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Da-Wu Zeng et al.
PloS one, 8(10), e77942-e77942 (2013-11-28)
This study aimed to investigate associations between ceruloplasmin (CP) levels, inflammation grade and fibrosis stages in patients with chronic hepatitis B (CHB) and to establish a noninvasive model to predict cirrhosis. Liver biopsy samples and sera were collected from 198
Marco Barbariga et al.
The Journal of biological chemistry, 289(6), 3736-3748 (2013-12-25)
Asparagine deamidation occurs spontaneously in proteins during aging; deamidation of Asn-Gly-Arg (NGR) sites can lead to the formation of isoAsp-Gly-Arg (isoDGR), a motif that can recognize the RGD-binding site of integrins. Ceruloplasmin (Cp), a ferroxidase present in the cerebrospinal fluid
Razvan T Dadu et al.
Circulation. Heart failure, 6(5), 936-943 (2013-07-19)
Ceruloplasmin (Cp) decreases nitric oxide bioavailability in blood and has been associated with cardiovascular disease (CVD) in clinical studies. We assessed the associations between Cp and incident heart failure (HF), death, and CVD in the Atherosclerosis Risk in Communities (ARIC)
Lingli Jiang et al.
American journal of physiology. Gastrointestinal and liver physiology, 301(5), G877-G886 (2011-08-20)
The Menkes copper ATPase (Atp7a) and metallothionein (Mt1a) are induced in the duodenum of iron-deficient rats, and serum and hepatic copper levels increase. Induction of a multi-copper ferroxidase (ceruloplasmin; Cp) has also been documented. These findings hint at an important
Perungavur N Ranganathan et al.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 25(4), 687-695 (2012-02-22)
Discovered over a decade ago, hephaestin (Heph) has been implicated as a ferroxidase (FOX) vital for intestinal iron absorption. Stringent structural or kinetic data derived from purified, native protein is however lacking, leading to the hypothesis that an alternate, undiscovered
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