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ligand
(Multimodal strong anion exchanger)
製造商／商標名
Cytiva 17371502
基質
high-flow agarose
樣品平均尺寸
40 μm (median particle size of the cumulative volume distribution)
cleaning in place
2-14
工作範圍
3-12
容量
45-85 mg Mab/ml binding capacity
一般說明
The multimodal anion exchanger ligand of Capto adhere ImpRes is immobilized to the base matrix and interacts with the target molecule through multiple types of interactions.
The high selectivity of the anion multimodal ligand allows operation in a variety of process conditions to solve challenging purification problems. Contaminants such as DNA, host cell proteins, leached protein A, aggregates, and viruses are efficiently removed.
Capto adhere ImpRes is available in a range of different bulk pack sizes for easy scale-up and pre-packed formats for process development.
As member of the BioProcess media range, Capto adhere ImpRes meets industrial demands with security of supply and comprehensive technical and regulatory support.
The high selectivity of the anion multimodal ligand allows operation in a variety of process conditions to solve challenging purification problems. Contaminants such as DNA, host cell proteins, leached protein A, aggregates, and viruses are efficiently removed.
Capto adhere ImpRes is available in a range of different bulk pack sizes for easy scale-up and pre-packed formats for process development.
As member of the BioProcess media range, Capto adhere ImpRes meets industrial demands with security of supply and comprehensive technical and regulatory support.
特點和優勢
Capto adhere ImpRes is a strong anion exchange multimodal BioProcess chromatography medium (resin), designed to meet the demands of modern large-scale manufacturers, for high-resolution polishing of monoclonal antibodies (MAbs) and other biomolecules.
- High yields achieved through the high-resolution beads and selectivity of the ligand.
- Efficient removal of aggregates, viruses, and main contaminants in MAb processes.
- Enables use of a platform approach to MAb process development.
- Allows separation of MAb charged variants.
儲存和穩定性
Store at 4 to 30 °C (20% ethanol)
分析報告
To view the Certificate of Analysis for this product, please visit www.cytiva.com.
訊號詞
Warning
危險聲明
儲存類別代碼
3 - Flammable liquids
商品
In these studies, the binding capacity for MAbs and the efficiency in the clearance of impurities using Capto adhere ImpRes in bind/elute mode was evaluated.
This page describes the maintenance of media and storage conditions for multimodal chromatography using GE Healthcare products.
实验方案
Capto adhere ImpRes is a cost-effective and flexible chromatography medium from GE Healthcare, designed for high-resolution polishing of MAbs.
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