跳转至内容
Merck

G9270

Sigma-Aldrich

γ-谷氨酰转肽酶 来源于马肾脏

Type VI, 5-12 units/mg solid

别名:

γ-谷氨酰转移酶, γ;-GT, GGTP, (5-谷氨酰)肽:氨基酸 5-谷氨酰转移酶

登录查看公司和协议定价


About This Item

CAS号:
EC號碼:
MDL號碼:
分類程式碼代碼:
12352204
NACRES:
NA.54

生物源

equine kidney

品質等級

種類

Type VI

形狀

solid

比活性

5-12 units/mg solid

儲存溫度

−20°C

一般說明

γ-谷氨酰转肽酶是一种异二聚酶,属于N端亲核水解酶超家族。

應用

来自马肾的γ-谷氨酰转肽酶已用于:

  • 鉴定河豚肝脏中4-S-半胱氨酸河豚毒素的形成
  • 作为标准品,用于测定人B细胞淋巴瘤细胞裂解物的γ -谷氨酰转移酶的活性
  • 解异肽,以研究其对微管蛋白聚集的影响

生化/生理作用

γ-谷氨酰转肽酶参与谷胱甘肽代谢,可以催化γ -谷氨酰化合物的裂解,如谷胱甘肽。它还对γ -谷氨酰基向氨基酸和多肽的转移发挥着作用。

品質

粗品

單位定義

在 25°C、pH 8.5 的条件下,一个单位每分钟从 L-γ-谷氨酰-β-硝基苯胺中释放出 1.0 μmol 对硝基苯胺。

抑制劑

产品编号
说明
价格

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本?

如果您需要特殊版本,可通过批号或批次号查找具体证书。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Karin Bracht et al.
Journal of cancer research and clinical oncology, 133(12), 957-967 (2007-06-15)
The aim of this study was to characterize three new, recently established non-Hodgkin lymphoma cell lines (GUMBUS, DOGUM, and DOGKIT), isolated from patients developing high-clinical resistance to cytotoxic therapy, with respect to sensitivity toward 21 antitumor drugs from different classes
Lawrence M Schopfer et al.
The Journal of biological chemistry, 293(35), 13566-13577 (2018-07-15)
Exposure to organophosphorus toxicants (OP) can have chronic adverse effects that are not explained by inhibition of acetylcholinesterase, the cause of acute OP toxicity. We therefore hypothesized that OP-induced chronic illness is initiated by the formation of organophosphorus adducts on
Gina Boanca et al.
The Journal of biological chemistry, 281(28), 19029-19037 (2006-05-05)
Gamma-glutamyltranspeptidase (gammaGT), a member of the N-terminal nucleophile hydrolase superfamily, initiates extracellular glutathione reclamation by cleaving the gamma-glutamyl amide bond of the tripeptide. This protein is translated as an inactive proenzyme that undergoes autoprocessing to become an active enzyme. The
Mathias Oertli et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(8), 3047-3052 (2013-02-06)
Infection with the gastric bacterial pathogen Helicobacter pylori is typically contracted in early childhood and often persists for decades. The immunomodulatory properties of H. pylori that allow it to colonize humans persistently are believed to also account for H. pylori's
R Foddis et al.
Giornale italiano di medicina del lavoro ed ergonomia, 34(3 Suppl), 565-567 (2013-02-15)
The GGT enzyme, considered for years only as a marker of liver disease and alcohol abuse, has now revealed a risk of death for many causes. Through a molecular exclusion chromatography on FPLC system (Fast Protein Liquid Chromatography), it is

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门