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Merck

G9003

Sigma-Aldrich

D-谷氨酰胺

≥98% (HPLC)

别名:

D -谷氨酸5-酰胺, D-2-氨基戊二酸

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About This Item

经验公式(希尔记法):
C5H10N2O3
CAS号:
分子量:
146.14
Beilstein:
1723796
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.32

product name

D-谷氨酰胺, ≥98% (HPLC)

品質等級

化驗

≥98% (HPLC)

形狀

powder

顏色

white

應用

cell analysis

SMILES 字串

N[C@H](CCC(N)=O)C(O)=O

InChI

1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m1/s1

InChI 密鑰

ZDXPYRJPNDTMRX-GSVOUGTGSA-N

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一般說明

谷氨酰胺是人体内存在的一种非必需的、最丰富的游离氨基酸。它是蛋白质的重要组成成分,是20种蛋白原氨基酸之一。它形成5-6%的结合氨基酸。

應用

D-谷氨酰胺已用于研究其在保护乙醛诱导的Caco-2细胞单层屏障功能破坏中的作用。

生化/生理作用

谷氨酰胺通过α-酮戊二酸和谷氨酸形成氨基酸转氨作用的中心代谢产物。这种氨基酸通过不同的酶代谢,例如存在于肝脏中的谷氨酰胺酶和存在于骨骼肌中的谷氨酰胺合成酶。在细胞质中由其他氨基酸产生,主要由支链氨基酸和谷氨酸产生。它在氨代谢和解毒中起着至关重要的作用。其骨骼肌水平在创伤、手术和炎症状态后显著降低。它可作为致命败血症的预后标志物,在此期间其骨骼肌水平降低了90%。

其他說明

谷氨酰胺的非天然异构体。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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American journal of physiology. Gastrointestinal and liver physiology, 287(3), G510-G517 (2004-08-28)
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