所有图片(1)
About This Item
经验公式（希尔记法）:
C10H12Li3N5O10P2S
CAS号:
分子量:
477.07
Beilstein:
8181243
MDL號碼:
分類程式碼代碼:
41106305
PubChem物質ID:
NACRES:
NA.77
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![鸟苷5′-[β,γ-亚氨基]三磷酸 三钠盐 水合物 ≥85% (HPLC), powder](/deepweb/assets/sigmaaldrich/product/structures/204/494/05808804-1ca7-44bf-b6c5-d4934dc7cb85/640/05808804-1ca7-44bf-b6c5-d4934dc7cb85.png)
化驗
≥85% (HPLC)
形狀
powder
顏色
white
溶解度
H2O: 20 mg/mL (Solutions are very unstable; prepare immediately prior to use.)
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
[Li+].[Li+].[Li+].NC1=Nc2c(ncn2[C@@H]3O[C@H](COP([O-])(=O)OP([O-])([O-])=S)[C@@H](O)[C@H]3O)C(=O)N1
InChI
1S/C10H15N5O10P2S.3Li/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(24-9)1-23-26(19,20)25-27(21,22)28;;;/h2-3,5-6,9,16-17H,1H2,(H,19,20)(H2,21,22,28)(H3,11,13,14,18);;;/q;3*+1/p-3/t3-,5-,6-,9-;;;/m1.../s1
InChI 密鑰
LMCWQGPJYZRMKU-CYCLDIHTSA-K
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相关类别
應用
鸟苷5′-[β-硫代]二磷酸三锂盐已作为G蛋白激活抑制剂，用于研究其对袋细胞神经元中的乙酰胆碱电流的影响。它还用于研究其对胆碱能依赖性平台期电位的影响。
生化／生理作用
鸟苷5′-[β-硫代]二磷酸是鸟苷的不可水解类似物，可用作G蛋白激活抑制剂。
特點和優勢
这种化合物是环核苷酸研究的特色产品。点击此处发现更多特色环核苷酸产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。
聯結
不可水解的 GDP 类似物
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
其他客户在看
A K H Tam et al.
Neuroscience, 179, 41-55 (2011-02-01)
Targeting signalling molecules to ion channels can expedite regulation and assure the proper transition of changes to excitability. In the bag cell neurons of Aplysia, single-channel studies of excised patches have revealed that protein kinase C (PKC) gates a non-selective
E Y Moon et al.
Life sciences, 86(17-18), 683-690 (2010-03-03)
We evaluated Gi-protein inhibitor, guanosine 5'-O-(2-thiodiphosphate)(GOT)-induced senescence-associated(SA)-beta-galactosidase(Gal) positive cell formation to determine if it occurred through phosphorylation of cyclic AMP-dependent response element binding protein (CREB). IMR-90 human lung fibroblast cells were used. SA-beta-Gal positive cells and senescence-associated heterochromatic foci (SAHF)
R J Ho et al.
Archives of biochemistry and biophysics, 251(1), 148-155 (1986-11-15)
Forskolin-activated adenylate cyclases (AC) in intact membranes, solubilized with Lubrol or eluted following adsorption on a forskolin-Sepharose column, were examined for inhibition by GDP and GDP beta S. AC in intact membranes of rat or rabbit adipocytes was activated by
G L Kucera et al.
Biochemical and biophysical research communications, 153(1), 417-421 (1988-05-31)
The inhibition by guanosine 5'-[beta-thio]diphosphate (GDP beta S) of phospholipase C was compared in intact and saponin-permeabilized human platelets in order to assess whether effects of GDP beta S on phospholipase C activation unrelated to guanine nucleotide binding function were
E Oberdisse et al.
Biochemical and biophysical research communications, 144(3), 1188-1196 (1987-05-14)
Guanosine 5'-O-thiotriphosphate (GTP gamma S) and thrombin stimulate the activity of phospholipase C in platelets that have been permeabilized with saponin and whose inositol phospholipids have been prelabeled with [3H]inositol. Ca2+ has opposite effects on the formation of [3H]inositol phosphates
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