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Merck

G6657

Sigma-Aldrich

(−)-倍儿茶酸

≥98% (HPLC)

别名:

(2S,3R)-2-(3,4,5-三羟基苯基)-3,4-二氢-1(2H)-苯并-3,5,7-三醇

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About This Item

经验公式(希尔记法):
C15H14O7
CAS号:
分子量:
306.27
MDL號碼:
分類程式碼代碼:
12352205
PubChem物質ID:
NACRES:
NA.77

品質等級

化驗

≥98% (HPLC)

溶解度

H2O: 5 mg/mL (heat 2-10 min at 105C)
alcohol: soluble

應用

metabolomics
vitamins, nutraceuticals, and natural products

儲存溫度

2-8°C

SMILES 字串

O[C@@H]1Cc2c(O)cc(O)cc2O[C@H]1c3cc(O)c(O)c(O)c3

InChI

1S/C15H14O7/c16-7-3-9(17)8-5-12(20)15(22-13(8)4-7)6-1-10(18)14(21)11(19)2-6/h1-4,12,15-21H,5H2/t12-,15+/m1/s1

InChI 密鑰

XMOCLSLCDHWDHP-DOMZBBRYSA-N

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一般說明

(−)-没食子儿茶素是一种多酚化合物,是存在于绿茶Camellia sinensis中主要的儿茶素之一。

應用

(−)-没食子儿茶素作为参考标准品的应用实例:
  • 高效液相色谱鉴定菠萝(Ananas comosus)中的多酚化合物
  • 高效液相色谱/光电二极管阵列检测(RP-HPLC/PDAD)分析绿茶Camellia sinensis来源的儿茶素特征
  • 作为参考标准品,用于通过高效液相色谱-四极杆飞行时间串联质谱(HPLC-qTOF-MS/MS)分析圆叶葡萄(muscadine grape) 杂交种的黄烷-3-醇(黄烷醇)类化合物特征

生化/生理作用

(−)-没食子儿茶素(GC)具有清除自由基的抗氧化特性。它也可抑制破骨细胞生成。没食子儿茶素可激发大肠杆菌抵抗紫外线诱导突变的抗突变活性。它也可抑制牙龈卟啉单胞菌在口腔上皮细胞上的生长和粘附。

其他說明

在绿茶中发现的多酚化合物。(−)-表没食子儿茶素的差向异构体。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Q Guo et al.
Biochimica et biophysica acta, 1427(1), 13-23 (1999-03-20)
The purpose of this study is to examine the relationship between the free radical scavenging activities and the chemical structures of tea catechins ((-)-epigallocatechin gallate (EGCG), (-)-epigallocatechin (EGC) and (-)-epicatechin (EC)) and their corresponding epimers ((-)-gallocatechin gallate (GCG), (-)-gallocatechin (GC)
Simultaneous analysis of individual catechins and caffeine in green tea
Goto T, et al.,
Journal of Chromatography A, 295-299 (1996)
Chun Hay Ko et al.
Journal of agricultural and food chemistry, 57(16), 7293-7297 (2009-08-06)
In this study, three tea catechins, epigallocatechin (EGC), gallocatechin (GC), and gallocatechin gallate (GCG), were investigated for their effects on bone metabolism. The effects of the tea catechins on bone formation were evaluated using cultured rat osteoblast-like osteosarcoma cell line
S Sakanaka et al.
Bioscience, biotechnology, and biochemistry, 60(5), 745-749 (1996-05-01)
Effects of polyphenolic compounds isolated from green tea (Camellia sinensis) on the growth and adherence of Porphyromonas gingivalis onto human buccal epithelial cells were investigated. Green tea polyphenols, especially (-)-epigallocatechin gallate (EGCg) which is a dominant component of tea polyphenols
Ruijie Liu et al.
Journal of chromatography. A, 1635, 461740-461740 (2020-12-04)
In this study, a novel at-line nanofractionation screening platform was successfully developed for the rapid screening and identification of α-glucosidase inhibitors from natural products. A time-course bioassay based on high density well-plates was performed in parallel with high resolution mass

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