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Merck

G1501

Sigma-Aldrich

L-谷氨酸 钾盐 一水合物

≥99% (HPLC), powder

别名:

2-氨基-5-羟基-5-氧基戊酸钾, MPG, 谷氨酸单钾, (S)-2-氨基戊二酸, L-α-氨基戊二酸 钾盐, L-2-氨基戊二酸 钾盐, L-谷氨酸钾, Glu

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About This Item

经验公式(希尔记法):
C5H8KNO4 · H2O
CAS号:
分子量:
203.23
Beilstein:
3637377
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.32

品質等級

化驗

≥99% (HPLC)

形狀

powder

顏色

white

SMILES 字串

O.[K+].N[C@@H](CCC([O-])=O)C(O)=O

InChI

1S/C5H9NO4.K.H2O/c6-3(5(9)10)1-2-4(7)8;;/h3H,1-2,6H2,(H,7,8)(H,9,10);;1H2/q;+1;/p-1/t3-;;/m0../s1

InChI 密鑰

XIBUKSQTWSKJMQ-QTNFYWBSSA-M

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一般說明

L-谷氨酸是哺乳动物中枢神经系统(CNS)中主要的兴奋性神经递质。它与膜结合的谷氨酸受体相互作用。在细胞培养中,谷氨酸钾也被用作MEM非必需氨基酸溶液的组成部分。

應用

使用L-谷氨酸钾盐一水合物
  • 在细胞培养中,MEM非必需氨基酸溶液的组成部分。
  • 用于纯化牛脑的微管蛋白。
  • 用于在形成双色极性标记荧光微管种子时在原液中制备淬火缓冲液。
  • 大肠杆菌菌株制备RF2(释放因子2)无细胞抽出物。
  • 拟南芥植物培养期间制备原液。

生化/生理作用

L-谷氨酸在发育、学习、记忆、可塑性和认知中起着关键作用。它在神经病理学疾病的发病机制中起着至关重要的作用,例如癫痫、精神分裂症、中风、缺血、肌萎缩侧索硬化症(amyotrophic lateral sclerosis),、廷顿舞蹈病和帕金森病。谷氨酸还负责长时程增强(LTP)和长时程抑郁(LTD)的激活。谷氨酸受体的诱导在偏头痛的病理生理学中起着关键作用。
红藻氨酸、NMDA和使君子氨酸受体的激动剂;兴奋性氨基酸神经递质。

特點和優勢

我们高纯度的L-谷氨酸钾盐一水合物将为您的纯化或制备神经病理疾病的研究需要提供支持

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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