G111080

DMT-dG（ib）亚磷酰胺

configured for PerkinElmer, configured for Polygen

• 别名: DMT-dG(ib)酰胺, N-（2-甲基-1-丙酮基）-5′-O-[双(4-甲氧苯基)苯甲基]-2′-脱氧鸟苷, 3′-[2-氰乙基N,N-双(1-甲基乙基)亚磷酰胺], N2-异丁酰-5′-O-(4,4′-双甲氧基三基)-2′-脱氧鸟苷-3′-O-[O-(2-氰乙基)-N,N′-二异丙基亚磷酰胺], 鸟嘌呤核苷5′-O-[双(4-甲氧苯基)苯甲基]-2′-脱氧胞-N-（2-甲基-1-丙酮基）-，3′-[2-氰乙基N,N-双(1-甲基乙基)亚磷酰胺]
• 经验公式（希尔记法）: C₄₄H₅₄N₇O₈P
• CAS号: 93183-15-4
• 分子量: 839.92
• MDL號碼: MFCD00055147
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329799727
• NACRES: NA.51

属性

• 生物源: non-animal source (no BSE/TSE risk)
• 種類: for DNA synthesis
• 產品線: Proligo Reagents
• 化驗: ≥99% (³¹P-NMR); ≥99.0% (reversed phase HPLC)
• 形狀: powder or granules
• 技術: oligo synthesis: suitable
• 雜質: ≤0.3 wt. % water content (Karl Fischer)
• 顏色: white to off-white
• &lambda ；: conforms (UV/VIS Identity)
• 相容性: configured for PerkinElmer; configured for Polygen
• 核苷譜: base: deoxyguanosine; base protecting group: isobutyryl; 2' protecting group: none; 5' protecting group: DMT; deprotection: standard
• 儲存溫度: 2-8°C
• SMILES 字串: COc1ccc(cc1)C(OC[C@H]2O[C@H](C[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)n3cnc4C(=O)NC(NC(=O)C(C)C)=Nc34)(c5ccccc5)c6ccc(OC)cc6
• InChI: 1S/C44H54N7O8P/c1-28(2)41(52)48-43-47-40-39(42(53)49-43)46-27-50(40)38-25-36(59-60(57-24-12-23-45)51(29(3)4)30(5)6)37(58-38)26-56-44(31-13-10-9-11-14-31,32-15-19-34(54-7)20-16-32)33-17-21-35(55-8)22-18-33/h9-11,13-22,27-30,36-38H,12,24-26H2,1-8H3,(H2,47,48,49,52,53)/t36-,37+,38+,60?/m0/s1
• InChI 密鑰: FDRMKYVTIFSDPR-MMROLVBFSA-N

说明

一般說明

Proligo′s DNA phosphoramidites lead to high-yield and high-quality oligonucleotides due to their high coupling efficiency. The deprotection step of automated oligonucleotide synthesis is integral to synthesis time and final product quality. Exocyclic amine functions are protected by a benzoyl group (dA(bz) and dC(bz)) or isobutyryl group (dG(ib)).

Key features of DNA phosphoramidites :

• Recommended cleavage and deprotection conditions are 8 hours at 55 °Cor 24 hours at room temperature using concentrated ammonia solution,for standard base-protected oligonucleotides
• The high coupling efficiency of Proligo′s DNA phosphoramidites leads tohigh-yield and high-quality oligonucleotidesThe product belongs to Expedite^™ and PolyGen^® synthesizers.

法律資訊

Expedite is a trademark of Applera Corporation or its subsidiaries in the US and/or certain other countries

PolyGen is a registered trademark of PolyGen GmbH.

安全信息

• 儲存類別代碼: 13 - Non Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable