推荐产品
product name
γ-Glu-Cys, ≥80% (HPLC)
品質等級
化驗
≥80% (HPLC)
形狀
powder
成份
Peptide content, ≥60% elemental analysis
技術
ligand binding assay: suitable
顏色
white to off-white
儲存溫度
−20°C
SMILES 字串
N[C@@H](CCC(=O)N[C@@H](CS)C(O)=O)C(O)=O
InChI
1S/C8H14N2O5S/c9-4(7(12)13)1-2-6(11)10-5(3-16)8(14)15/h4-5,16H,1-3,9H2,(H,10,11)(H,12,13)(H,14,15)/t4-,5-/m0/s1
InChI 密鑰
RITKHVBHSGLULN-WHFBIAKZSA-N
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相关类别
Amino Acid Sequence
Glu-Cys
應用
γ-Glu-Cys可用于研究谷胱甘肽合成酶的活性位点和动力学。它也被用于从拟南芥 组织中提取和量化低分子量硫醇。
生化／生理作用
γ-L-谷氨酰基-L-半胱氨酸（γ-Glu-Cys）是用于通过谷胱甘肽合成酶生物合成L-谷胱甘肽的底物。γ-Glu-Cys通过裂解谷胱甘肽的Cys-Gly肽键而产生。它对植物螯合素的形成也是必需的，植物螯合素是富含半胱氨酸的硫醇反应性肽。
外觀
从0.1％TFA中冻干获得。
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
Runa Njålsson et al.
Human genetics, 116(5), 384-389 (2005-02-18)
Glutathione synthetase (GS) deficiency is a rare autosomal recessive disorder. The clinical phenotype varies widely, and nearly 30 different mutations in the GSS gene have been identified. In the present study, genotype, enzyme activity, metabolite levels and clinical phenotype were
H Yamaguchi et al.
Journal of molecular biology, 229(4), 1083-1100 (1993-02-20)
Glutathione synthetase (gamma-L-glutamyl-L-cysteine: glycine ligase (ADP-forming) EC 6.3.2.3: GSHase) catalyzes the synthesis of glutathione from gamma-L-glutamyl-L-cysteine and Gly in the presence of ATP. The enzyme from Escherichia coli is a tetramer with four identical subunits of 316 amino acid residues.
Xueni Sun et al.
Analytica chimica acta, 1080, 127-137 (2019-08-15)
Glutathione is an essential intra- and extracellular antioxidant. The level of glutathione in the body is highly related to different disease states and is a useful indicator of disease risk and oxidative stress status. We have developed a sensitive, selective
Hemantaranjan, A.
Advances In Plant Physiology (2012)
Chava B Pocernich et al.
Biochimica et biophysica acta, 1822(5), 625-630 (2011-10-22)
Oxidative stress has been associated with the onset and progression of mild cognitive impairment (MCI) and Alzheimer disease (AD). AD and MCI brain and plasma display extensive oxidative stress as indexed by protein oxidation, lipid peroxidation, free radical formation, DNA
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