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Merck

F6889

Sigma-Aldrich

法莫替丁

别名:

N′-(氨基磺酰基)-3-([2-(二氨基亚甲基氨基)-4-噻唑基]甲硫基)丙脒

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About This Item

经验公式(希尔记法):
C8H15N7O2S3
CAS号:
分子量:
337.45
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

品質等級

起源

Johnson & Johnson

SMILES 字串

N\C(N)=N\c1nc(CSCCC(=N)NS(N)(=O)=O)cs1

InChI

1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)

InChI 密鑰

XUFQPHANEAPEMJ-UHFFFAOYSA-N

基因資訊

human ... HRH2(3274)

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應用

法莫替丁已用于测试其对HEK293膜中转染的人ether-a-go-go相关基因(hERG)结合的效应。它也被用于基于聚己内酯的药物递送研究。

生化/生理作用

H2组胺受体拮抗剂;抗溃疡剂。
法莫替丁对毒蕈碱和烟碱样受体无效。它竞争性地抑制胃酸的分泌,并引发粘膜损伤保护。

特點和優勢

该化合物由 Johnson & Johnson 开发。想要浏览其他由制药公司开发的化合物以及已批准药物/候选药物清单, 请单击此处

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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