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Merck
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Key Documents

EMU090681

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Xrn1

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About This Item

分類程式碼代碼:
41105324
NACRES:
NA.51

描述

Powered by Eupheria Biotech

品質等級

100

產品線

MISSION®

形狀

lyophilized powder

esiRNA cDNA 標靶序列

TGGGAAAGGCAGTCTTTGTTAACTGGCCTCATCTTGAAGAAGCTAGAGTTGTGGCAGTATCAGATGGTGAAACTAAGTTTTACATAGAAGAACCTCCAGGAACACAGAAGGTTTATTTGGGAAAAACTGCCCCACCATCTAAAGTCATCCAACTTACAGATAAAGAACAATCGAACTGGACTAAAGAAATACAAGGAATTTCAGAACAATATCTAAGAAGAAAGGGAATAATAATAAATGAAACATCTGCTGTTGTGTATGCTCAGTTGCTCACGGGTCGTAAATATCAAATCAGTCAGAATGGTGAAGTTCGTCTAGAAAAACAGTGGTCAAAACAAATTCTTCCTTTTGTTTATCAAACTATTGTTAAGGACATCCGAGCTTTTGACTCTCGTTTCTCCAATATCAAGACATTGGATGACTTGTTTCCACCGAGAACTATGGTCTTTATGCTTGGAACTCCTTATTATGGCTGCACTGGAGAAGTTCAGGATTCAGGAGACTTGATTACAGAAGGGAGAATTCGTGTGGTTTTCAGCATTCCATGTGAGCCAAATCTTGATGC

Ensembl | 小鼠類登錄號

ENSMUSG00000032410

NCBI登錄號

NM_011916

運輸包裝

ambient

儲存溫度

−20°C

基因資訊

mouse ... XRN1(24127) , Xrn1(24127)

相关类别

一般說明

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律資訊

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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Shin-Ichiro Hori et al.
Biochemical and biophysical research communications, 464(2), 506-511 (2015-07-15)
Antisense oligonucleotides (ASOs) can suppress the expression of a target gene by cleaving pre-mRNA and/or mature mRNA via RNase H1. Following the initial endonucleolytic cleavage by RNase H1, the target RNAs are degraded by a mechanism that is poorly understood.
Oussama Meziane et al.
Scientific reports, 5, 16688-16688 (2015-11-21)
The decapping scavenger enzyme DcpS is known for its role in hydrolyzing the cap structure following mRNA degradation. Recently, we discovered a new function in miRNA degradation activation for the ortholog of DcpS in C. elegans. Here we show that

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