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Merck
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主要文件

EMU073461

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Mkl1

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About This Item

分類程式碼代碼:
41105324
NACRES:
NA.51

描述

Powered by Eupheria Biotech

品質等級

100

產品線

MISSION®

形狀

lyophilized powder

esiRNA cDNA 標靶序列

GAGCAGAGAAGAAGCCTGGAGCGGGCCAGGACCGAGGACTATTTGAAACGGAAGATCCGTTCCCGGCCCGAGAGAGCAGAGCTGGTCAGGATGCACATTCTGGAAGAGACCTCGGCTGAGCCTTCGCTCCAGGCCAAGCAGCTGAAGCTGAAGAGAGCCAGGCTGGCTGATGACCTCAATGAAAAGATTGCACAGAGGCCTGGCCCCATGGAGCTGGTGGAGAAGAATATCCTGCCTGTGGAGTCCAGCCTGAAGGAGGCTATCATTGTGGGCCAGGTAAATTACCCAAAGGTAGCAGACAGTTCCTCCTTCGACGAGGACAGCAGCGATGCCCTGTCTCCTGAGCAGCCTGCCAGCCATGAGTCCCAGGGTTCAGTGCCATCACCCTTGGAGTCCCGAGTCAGTGATCCACTGCCCAGTGCCACCTCCATATCACC

Ensembl | 小鼠類登錄號

ENSMUSG00000042292

NCBI登錄號

NM_153049

運輸包裝

ambient

儲存溫度

−20°C

基因資訊

mouse ... MKL1(223701) , Mkl1(223701)

一般說明

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律資訊

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

閃點（°F）

Not applicable

閃點（°C）

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
VYS
XWR

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Xu Shiwen et al.
PloS one, 10(5), e0126015-e0126015 (2015-05-09)
In scleroderma (systemic sclerosis, SSc), persistent activation of myofibroblast leads to severe skin and organ fibrosis resistant to therapy. Increased mechanical stiffness in the involved fibrotic tissues is a hallmark clinical feature and a cause of disabling symptoms. Myocardin Related
Philipp Kircher et al.
Science signaling, 8(402), ra112-ra112 (2015-11-12)
Megakaryoblastic leukemia 1 (MKL1) is a coactivator of serum response factor (SRF) that promotes the expression of genes associated with cell proliferation, motility, adhesion, and differentiation-processes that also involve dynamic cytoskeletal changes in the cell. MKL1 is inactive when bound

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