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Merck
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Key Documents

EMU022811

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Iws1

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About This Item

分類程式碼代碼:
41105324
NACRES:
NA.51

描述

Powered by Eupheria Biotech

產品線

MISSION®

形狀

lyophilized powder

esiRNA cDNA 標靶序列

TGAAGATTCGGGAGGAATTGTTAAAGATTCTGCAAGAGCTACCTAGTGTGAGCCAAGAGACCCTGAAGCATAGTGGGATTGGCCGAGCAGTGATGTATCTGTATAAACACCCTAAGGAATCAAGGTCCAACAAGGATATGGCAGGGAAGCTCATCAATGAGTGGTCTCGGCCCATATTTGGTCTTACCTCAAACTATAAAGGAATGACAAGAGAAGAAAGGGAACAGAGAGATCTAGAACAAATGCCACAGCGACGAAGATTGAGCAGCACTGGTGGTCAGACACCACGAAGAGACCTGGAGAAGGTCCTAACAGGAGAAGAAAAGGCTCTTAGACCTGGAGATCCTGGCTTCTGTGCCCGTGCAAGAGTCCCAATGCCATCAAACAAGGACTATGTTGTCAGGCCCAAGTGGAATGTAGAAATGGAGTCATCCAGGTTTCAGGCAT

Ensembl | 小鼠類登錄號

ENSMUSG00000024384

NCBI登錄號

NM_173441

運輸包裝

ambient

儲存溫度

−20°C

基因資訊

mouse ... IWS1(73473) , Iws1(73473)

一般說明

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律資訊

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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Reza K Oqani et al.
Scientific reports, 9(1), 3831-3831 (2019-03-09)
The mRNA processing and export factor, Iws1, interacts with the histone H3/H4 chaperone, Spt6 (Supt6 in mouse gene ontology) and recruits the lysine methyltransferase, Setd2, to chromatin to regulate H3K36me3. This recruitment is known to be crucial for pre-mRNA splicing

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