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形狀
solid
雜質
Other adenosine phosphates, essentially free
儲存溫度
−20°C
SMILES 字串
N.Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(=O)OP(O)(=O)OCC4OC(C(O)C4O)n5cnc6c(N)ncnc56)C(O)C3O
InChI
1S/C20H27N10O16P3.H3N/c21-15-9-17(25-3-23-15)29(5-27-9)19-13(33)11(31)7(43-19)1-41-47(35,36)45-49(39,40)46-48(37,38)42-2-8-12(32)14(34)20(44-8)30-6-28-10-16(22)24-4-26-18(10)30;/h3-8,11-14,19-20,31-34H,1-2H2,(H,35,36)(H,37,38)(H,39,40)(H2,21,23,25)(H2,22,24,26);1H3
InChI 密鑰
PKSQTRWRSNNYCW-UHFFFAOYSA-N
相关类别
應用
P1,P3-Di(adenosine-5′) triphosphate (Ap3A) is a diadenosine oligophosphate (ApnA) family member. ApnAs have been found to act as a signaling molecule.
P1,P3-Di(adenosine-5′) triphosphate ammonium salt has been used as a component of the incubation medium for incubating fibroblast cell lines for FoF1 ATP-synthase activity.
數量
Approx. 25 A260 units per mg.
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
The FEBS journal, 273(15), 3534-3544 (2006-08-04)
Heat shock inducible lysyl-tRNA synthetase of Escherichia coli (LysU) is known to be a highly efficient diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) synthase. However, we use an ion-exchange HPLC technique to demonstrate that active LysU mixtures actually have a dual catalytic activity, initially
Archives of biochemistry and biophysics, 433(1), 129-143 (2004-12-08)
Nudix hydrolases catalyze the hydrolysis of nucleoside diphosphates linked to other moieties, X, and contain the sequence motif or Nudix box, GX(5)EX(7)REUXEEXGU. The mechanisms of Nudix hydrolases are highly diverse in the position on the substrate at which nucleophilic substitution
Vascular pharmacology, 48(4-6), 157-164 (2008-03-08)
Diadenosine polyphosphates (Ap(n)A) are released by degranulating platelets and high, local concentrations may form at sites of platelet activation. Radial artery grafts, now often used alongside the internal mammary artery in coronary artery bypass surgery, are particularly reactive to several
Current medicinal chemistry. Cardiovascular and hematological agents, 1(2), 151-169 (2004-08-24)
Diadenosine polyphosphates (Ap(n)A) are naturally occurring molecules which have been identified in human and guinea-pig cardiac tissue and whose physiological role is being established. They are stored in platelet dense granules in a metabolically inactive form. Ap(n)A form a class
Journal of cellular physiology, 208(2), 274-281 (2006-03-21)
FHIT is a tumor suppressor gene that is frequently inactivated in human cancer. Although the Fhit protein is known to hydrolyze diadenosine triphosphate (Ap(3)A), this hydrolase activity is not required for Fhit-mediated oncosuppression. Indeed, the molecular mechanisms and the regulatory
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