推荐产品
生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
33 kDa
物種活性
dog, guinea pig, human, horse, sheep, bovine, rat
濃度
0.5 mg - 1 mg/mL
技術
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... ACVR2B(93)
免疫原
Synthetic peptide directed towards the C terminal region of human ACVR2B
應用
Anti-ACVR2B antibody produced in rabbit is suitable for western blotting at a concentration of 0.25μg/ml.
生化／生理作用
Activin A receptor, type IIB (ACVR2B) binds activin ligands that promote growth and differentiation via the TGF-β signaling. ACVR2B is expressed in adult hypothalamus and forebrain. Activin receptors IIA and IIB may regulate germ cell proliferation in the human ovary during primordial follicle formation and in mouse testis.
序列
Synthetic peptide located within the following region: HDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI
外觀
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
S J Martins da Silva et al.
Developmental biology, 266(2), 334-345 (2004-01-24)
The formation of the essential functional unit of the ovary, the primordial follicle, occurs during fetal life in humans. Factors regulating oogonial proliferation and interaction with somatic cells before primordial follicle formation are largely unknown. We have investigated the expression
Sirisha H S Mendis et al.
Biology of reproduction, 84(2), 379-391 (2010-10-12)
Activin affects many aspects of cellular development, including those essential for reproductive fitness. This study examined the contribution of activin A to murine fetal testicular development, revealing contrasting outcomes of activin actions on Sertoli cells and gonocytes. Shortly after sex
M C Miller et al.
Journal of neuroendocrinology, 24(6), 962-972 (2012-02-03)
The inhibin/activin family of proteins is known to have a broad distribution of synthesis and expression in many species, as well as a variety of functions in reproductive and other physiological systems. Yet, our knowledge regarding the production and function
Varuna C Banduseela et al.
Physiological genomics, 45(12), 477-486 (2013-04-11)
Critical illness myopathy (CIM) is characterized by a preferential loss of the motor protein myosin, muscle wasting, and impaired muscle function in critically ill intensive care unit (ICU) patients. CIM is associated with severe morbidity and mortality and has a
Se-Jin Lee et al.
Proceedings of the National Academy of Sciences of the United States of America, 102(50), 18117-18122 (2005-12-07)
Myostatin is a secreted protein that normally functions as a negative regulator of muscle growth. Agents capable of blocking the myostatin signaling pathway could have important applications for treating human muscle degenerative diseases as well as for enhancing livestock production.
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