化驗
≥95% (HPLC)
形狀
powder
顏色
white
儲存溫度
−20°C
SMILES 字串
CC(C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)Nc2ccc3c(OC(=O)C=C3C(F)(F)F)c2
InChI
1S/C33H36F3N5O10/c1-15(2)28(41-31(49)23(38-17(4)42)11-18-5-8-20(43)9-6-18)32(50)37-16(3)29(47)40-24(14-26(44)45)30(48)39-19-7-10-21-22(33(34,35)36)13-27(46)51-25(21)12-19/h5-10,12-13,15-16,23-24,28,43H,11,14H2,1-4H3,(H,37,50)(H,38,42)(H,39,48)(H,40,47)(H,41,49)(H,44,45)/t16-,23-,24-,28-/m0/s1
InChI 密鑰
GWKJISJKNKIJNP-DEQDFGQZSA-N
基因資訊
human ... CASP1(834) , CASP4(837)
mouse ... CASP1(12362) , CASP4(12363)
rat ... CASP1(25166) , CASP4(114555)
Amino Acid Sequence
NAc-Tyr-Val-Ala-Asp-AFC
基底
Membrane-permeable fluorogenic substrate for caspase 1 (ICE) and caspase 4 (TX).
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
Hsin-Ying Wu et al.
Particle and fibre toxicology, 10, 46-46 (2013-09-21)
Superparamagnetic iron oxide nanoparticles (IONPs) have been used as magnetic resonance imaging contrast agents for various research and diagnostic purposes, such as the detection of neuroinflammation and blood-brain-barrier integrity. As the central resident macrophage-like cells, microglia are responsible for managing
Emma M Creagh et al.
PloS one, 4(3), e5055-e5055 (2009-03-31)
Members of the caspase family of cysteine proteases coordinate cell death through restricted proteolysis of diverse protein substrates and play a conserved role in apoptosis from nematodes to man. However, while numerous substrates for the mammalian cell death-associated caspases have
R A Jones et al.
Hepatology (Baltimore, Md.), 27(6), 1632-1642 (1998-06-10)
The mechanism of Fas antigen-induced hepatocyte apoptosis was investigated. Using a monoclonal antibody directed against the Fas antigen, apoptosis was induced in freshly isolated murine hepatocytes within 90 minutes of antibody addition as assessed by plasma membrane bleb formation, chromatin
Gustavo Lemos Rocha et al.
Plant science : an international journal of experimental plant biology, 288, 110232-110232 (2019-09-16)
Seed coat is the tissue which establishes an interface between the seed inner tissues and external environment. Our group has shown that cowpea seed coat undergoes coordinated events of programmed cell death (PCD) during development. In relation to germinating seed
Peng Yin et al.
Acta neuropathologica, 137(6), 919-937 (2019-02-28)
The cytoplasmic accumulation of the nuclear TAR DNA-binding protein 43 (TDP-43) is a pathologic hallmark in amyotrophic lateral sclerosis, frontotemporal lobar degeneration, and other neurological disorders. However, most transgenic TDP-43 rodent models show predominant nuclear distribution of TDP-43 in the
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