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About This Item
经验公式（希尔记法）:
C8H7N3O2
CAS号:
分子量:
177.16
Beilstein:
164804
MDL號碼:
分類程式碼代碼:
12352204
PubChem物質ID:
NACRES:
NA.83
推荐产品
product name
4-氨基邻苯二甲酰肼,
化驗
≥98% (HPLC)
品質等級
形狀
powder
mp
300 °C (lit.)
溶解度
2 M NH4OH: 50 mg/mL, clear to slightly hazy
SMILES 字串
Nc1ccc2C(=O)NNC(=O)c2c1
InChI
1S/C8H7N3O2/c9-4-1-2-5-6(3-4)8(13)11-10-7(5)12/h1-3H,9H2,(H,10,12)(H,11,13)
InChI 密鑰
HUDPLKWXRLNSPC-UHFFFAOYSA-N
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應用
4-氨基邻苯二甲酰肼（异鲁米诺）已用于：
- 假结核耶氏菌感染后骨髓(BM)中性粒细胞的化学发光法活性氧(ROS)检测
- 克雷伯氏肺炎菌(K. pneumonia)暴露后中性粒细胞的活性氧检测
- 甲酰-蛋氨酸-亮氨酸-脯氨酸刺激后中性粒细胞的活性氧检测
生化／生理作用
4-氨基邻苯二甲酰肼或异鲁米诺是由酞嗪环构成的化学发光试剂，亲水性更高于鲁米诺。异鲁米诺在商业上广泛用于各种体外免疫分析，是可用于研究活性氧的放大性化学发光试剂。异鲁米诺也可用作电发光生物传感器(ECL)和微生物快速检测探针。
特點和優勢
能发出化学荧光。
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
M Rájecký et al.
International journal of laboratory hematology, 34(2), 136-142 (2011-08-13)
The differentiation between extra- and intracellular production of reactive oxygen species (ROS) in whole blood was measured by luminol- and isoluminol-enhanced chemiluminescence (CL). Azide (total CL inhibition), azide + horseradish peroxidase (HRP, restoring extracellular CL), superoxide dismutase + catalase (depleting
Chiedzo M Mpofu et al.
Gastroenterology, 133(5), 1487-1498 (2007-10-09)
Crohn's disease (CD) is mimicked by inherited phagocyte disorders and is associated with circulating antibodies against yeast mannan (anti-Saccharomyces cerevisiae antibody; ASCA). We speculated that mannans might impair phagocyte function. S cerevisiae mannan was assessed for its effects on human
Zian Lin et al.
Analytical chemistry, 78(15), 5322-5328 (2006-08-02)
A new method for pressurized capillary electrochromatography (pCEC) coupling with chemiluminescence (CL) detection using a modified on-column coaxial flow detection interface was developed. To evaluate the feasibility and reliability of the experimental setup, the typical CL compounds luminol and isoluminol
Chien-Wen S Kuo et al.
Journal of immunology (Baltimore, Md. : 1950), 187(1), 361-371 (2011-06-08)
Infection of human cells by human T cell leukemia virus type 1 (HTLV-1) is mediated by the viral envelope glycoproteins. The gp46 surface glycoprotein binds to cell surface receptors, including heparan sulfate proteoglycans, neuropilin 1, and glucose transporter 1, allowing
Maria Dahlberg et al.
Luminescence : the journal of biological and chemical luminescence, 23(3), 139-143 (2008-05-03)
Chemiluminescence systems enhanced by either isoluminol or luminol in combination with a peroxidase are sensitive methods for the detection of reactive oxygen species (ROS) generated by phagocyte NADPH oxidase. The two amplifying substrates are structurally very similar, differing only in
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