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生物源
goat
品質等級
共軛
agarose conjugate
抗體表格
affinity isolated antibody
抗體產品種類
secondary antibodies
無性繁殖
polyclonal
形狀
suspension
物種活性
mouse
標籤範圍
≥5 mg per mL
技術
Ouchterlony double diffusion: suitable
immunoprecipitation (IP): suitable
基質
Cross-linked 4% beaded agarose
基質活化
cyanogen bromide
基質墊片
1 atom
容量
0.4 mg/mL, resin binding capacity (mouse IgG)
儲存溫度
2-8°C
目標翻譯後修改
unmodified
一般說明
Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. An immunoglobulin has two heavy chains and two light chains connected by a disulfide bond. It mainly helps in immune defense. It is a glycoprotein. IgG is a major class of immunoglobulin. Mice consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE.
Immunoglobulin G (IgG) is a glycoprotein antibody that regulates immune responses such as phagocytosis and is also involved in the development of autoimmune diseases. Mouse IgGs have four distinct isotypes, namely, IgG1, IgG2a, IgG2b, and IgG3. IgG1 regulates complement fixation in mice. Goat Anti-Mouse IgG (whole molecule)-Agarose antibodies bind to all mouse IgG subclasses.
免疫原
IgG isolated from pooled normal mouse serum
應用
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Chromatin immunoprecipitation (1 paper)
Immunoprecipitation (1 paper)
Chromatin immunoprecipitation (1 paper)
Immunoprecipitation (1 paper)
Goat Anti-Mouse IgG (whole molecule)-Agarose antibodies have been used for immunoprecipiation assays. The product can also be used for Ouchterlony double diffusion applications.
Soluble antigens from meningococci extracts were mixed with ascitic fluid containing primary antibody and 50 μl of agarose-linked goat anti-mouse IgG for 5 hours at 4 °C.
生化／生理作用
IgG helps in opsonization, complement fixation and antibody-dependent cell-mediated cytotoxicity. Immunoglobulin G (IgG) participates in hypersensitivity type II and type III. IgG2a of IgG has cytotropic properties and IgG2 molecules have the ability to activate complement.
外觀
Suspension in 0.5 M NaCl containing preservative
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
其他客户在看
Nezlin R
The Immunoglobulins: Structure and Function (1998)
F. Calabi and M.S. Neuberger
Molecular Genetics of Immunoglobulin (1987)
C R Tinsley et al.
Journal of general microbiology, 138(11), 2321-2328 (1992-11-01)
The neisserial Lip antigen is a conserved antigen associated with the pathogenic Neisseria species, and is composed of multiple repeats of a consensus pentapeptide. A series of monoclonal antibodies reacting with meningococcal Lip antigen were subjected to epitope mapping, using
Suckow M A, et al.
The Laboratory Rat (2005)
Bidyut Ghosh et al.
The Biochemical journal, 393(Pt 3), 679-685 (2005-10-06)
In the developing pancreas, the onset of exocrine differentiation is driven by the activity of the PTF1 (pancreas transcription factor 1) transcriptional complex, which is comprised of the class II bHLH (basic helix-loop-helix) protein, Ptf1-p48 [also known as Ptf1a (pancreas
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