推荐产品
生物源
mouse
共軛
alkaline phosphatase conjugate
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
9E10, monoclonal
形狀
buffered aqueous glycerol solution
物種活性
human
技術
ELISA: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: 1:100 using a myc-tagged fusion protein.
同型
IgG1
UniProt登錄號
儲存溫度
2-8°C
目標翻譯後修改
unmodified
基因資訊
human ... MYC(4609)
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一般說明
Monoclonal Anti-c-myc (mouse IgG1 isotype) is derived from the 9E10 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized BALB/c mouse. The c-myc gene encodes for a protein of 62kDa called p62c-myc is associated mainly with cell nuclei.
免疫原
人p62c-Myc蛋白的合成肽。
應用
Anti-c-Myc-Alkaline Phosphatase antibody has been used in
- enzyme linked immunosorbent assay (ELISA)
- immunohistochemical labeling
- immunostaining
- western blotting
Monoclonal Anti-c-Myc-Alkaline Phosphatase antibody can be used for western blot assays at 1:100, using myc-tagged fusion proteins. The antibody can also be used for immunohistochemical applications.
生化／生理作用
The c-myc oncogene product(p62c-myc) exerts normal and oncogenic cellular functions. Elevated level of c-myc protein in malignant tissues when compared with normal tissue, but with the unexpected finding of a cytoplasmic accumulation of the protein in these tumors.
外觀
Solution in 0.05 M Tris buffer, containing 1% bovine serum albumin, 1 mM MgCl2, 50% glycerol, and 15 mM sodium azide.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Structural and functional insights into the lipopolysaccharide ABC transporter LptB 2 FG
Dong H, et al.
Nature Communications, 8(1), 222-222 (2017)
Ubiquitin ligase SYVN1/HRD1 facilitates degradation of the SERPINA1 Z variant alpha-1-antitrypsin Z variant via SQSTM1/p62-dependent selective autophagy
Feng,L, et al.
Autophagy, 13(4), 686-702 (2017)
Novel ganglioside antigen identified by B cells in human medullary breast carcinomas: the proof of principle concerning the tumor-infiltrating B lymphocytes
Kotlan B, et al.
Journal of Immunology, 175(4), 2278-2285 (2005)
Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.
Evan G I, et al.
Molecular and Cellular Biology, 5(12), 3610-3616 (1985)
Beatrix Kotlan et al.
Journal of immunology (Baltimore, Md. : 1950), 175(4), 2278-2285 (2005-08-06)
The potential tumor-recognizing capacity of B cells infiltrating human breast carcinoma is an important aspect of breast cancer biology. As an experimental system, we used human medullary breast carcinoma because of its heavy B lymphocytic infiltration paralleled to a relatively
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